Ispitivanje protuupalne aktivnosti odabranih biljnih vrsta

master's thesis

• Title (english): Examination of anti-inflammatory activity of selected plant species
• Author: Nikolina Lovrić
• Mentor: Marijana Zovko Končić (mentor)
• Committee member: Marijana Zovko Končić (predsjednik povjerenstva)
• Committee member: Maja Bival Štefan (član povjerenstva)
• Committee member: Jasna Jablan (član povjerenstva)
• Granter: University of Zagreb; Faculty of Pharmacy and Biochemistry; (Department of pharmacognosy); Zagreb
• Defense date and country: 2020-09-30, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Pharmacy; Pharmacy

Abstract

U ovome diplomskom radu istražena je protuupalna aktivnost ekstrakata biljnih droga Glycyrrhizae radix, Berberidis radicis cortex, Sylibi maiani fructus i Ehinaceae purpureae herba. Ekstrakti biljnih droga pripremljeni su u netkosičnom biorazgradivom glicerolu. Ispitana je povezanost dobivenih rezultata protuupalnog djelovanja sa sadržajem glicerola i flavonoida u ispitivanim ekstraktima. Rezultati ispitivanja pokazali su znatnu protuupalnu aktivnost biljne droge Glycyrrhizae radix u odnosu na pozitivnu kontrolu, te se to djelovanje može povezati sa sadržajem flavonoida. Preostali biljni ekstrakti pokazali su blago ili pak neznatno djelovanje te nizak sadržaj flavonoida.

Abstract (english)

In this work, anti-inflammatory activity of extracts of herbal drugs Glycyrrhizae radix, Berberidis radicis cortex, Silybi mariani fructus and Ehinaceae purpureae herba was investigated. Herbal drug extracts were prepared in a non-toxic biodegradable solvent glycerol. The correlation of the anti-inflammatory action and flavonoid content in the extracts was investigated. The results show that Glycyrrhizae radix demonstrated significant anti-inflammatory activity in relation to the positive control, and that this action can be associated with the content of flavonoids. The remaining plant extracts showed a slight or insignificant effect and a low content of flavonoids.

• Keywords: sladić; žutika; sikavica; Ehinacea; flavonoidi; protuupalna aktivnost
• Keywords (english): liquorice; barberry; silymarin; Echinacea; antiinflammatory activity
• Language: croatian
• URN:NBN: urn:nbn:hr:163:978200
• Study programme: Title: Pharmacy; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access; Embargo expiration date: 2022-09-30
• Created on: 2022-03-04 14:04:10