master's thesis
Historical use of cinchona tree

Petra Biliškov (2015)
Sveučilište u Zagrebu
Farmaceutsko-biokemijski fakultet
Zavod za farmakognoziju
Metadata
TitlePrimjena kininovca kroz povijest
AuthorPetra Biliškov
Mentor(s)Sanda Vladimir-Knežević (thesis advisor)
Abstract
Kininovac je biljka koja se stoljećima primjenjivala u liječenju malarije i za izolaciju kinina. Potječe iz Južne Amerike, ali se tijekom svoje bogate povijesti uzgojem proširio i u druge dijelove svijeta. Za antimalarično djelovanje kininovčeve kore odgovoran je alkaloid kinin. Kininovac je velikim dijelom zaslužan za suzbijanje malarije, bolesti koja je godinama bila uzrok smrti ljudi diljem svijeta, a danas se smatra bolešću tropskog područja. Unatoč razvoju novih sintetskih antimalarika učinkovitijih od kinina, zbog pojave rezistencije na novu generaciju lijekova, kinin se i dalje koristi za suzbijanje malarije u područjima gdje je ta bolest još uvijek raširena.
Keywordscinchona tree quinin malaria
Parallel title (English)Historical use of cinchona tree
Committee MembersSanda Vladimir-Knežević
Biljana Blažeković
Jadranka Vuković Rodriguez
GranterSveučilište u Zagrebu
Farmaceutsko-biokemijski fakultet
Lower level organizational unitsZavod za farmakognoziju
PlaceZagreb
StateCroatia
Scientific field, discipline, subdisciplineBIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Study programme typeuniversity
Study levelintegrated undergraduate and graduate
Study programmePharmacy
Academic title abbreviationmag. pharm.
Genremaster's thesis
Language Croatian
Defense date2015-09-25
Parallel abstract (English)
Cinchona tree is a plant used for several centuries in malaria treatment and isolation of quinine. It originates from South America, but in the course of its rich history, it has been cultivated around the world. The antimalaric property of cinchona bark is due to the alkaloid quinine. We have to thank to cinchona tree for uprooting malaria, a disease that was the cause of death of many people around the world and is now considered to be the disease of the tropical area specifically. Dispite the development of the synthetic antimalarials, which were better and stronger than quinine itself, because of the emergence of resistance to these new drugs, quinine is still used for the suppression of malaria in areas where the disease still prevails.
Parallel keywords (Croatian)kininovac kinin malarija
Resource typetext
Access conditionAccess restricted to students and staff of home institution
Terms of usehttp://rightsstatements.org/vocab/InC/1.0/
URN:NBNhttps://urn.nsk.hr/urn:nbn:hr:163:031031
CommitterPetra Gašparac