Citokrom P450 i metabolizam lijekova - značenje i novosti

Professional paper - Review paper

• Author: Mirela Lozić
• Author: Hrvoje Rimac
• Author: Mirza Bojić
• Author's institution: University of Zagreb; Faculty of Pharmacy and Biochemistry; (Department of medicinal chemistry)
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Pharmacy; Pharmacy

Abstract (english)

Cytochrome P450 enzymes are the most important enzyme superfamily for
metabolism of xenobiotics. In the last few years, knowledge on metabolism of xenobiotics
has grown exponentially. In this paper cytochrome P450 I A2, 2A6, 2C8,
2C9, 2C 19, 206, 2E I , 3A4 and 3A5 substrates, inhibitors and inductors are reviewed
with special focus on marker reactions of individual P4 50s.

• Keywords (croatian): citokrom P450; metabolizam lijekova; biotransformacija lijekova
• Language: croatian
• Publication type: Professional paper - Review paper
• Publication status: Published
• Peer review: Peer review - domestic
• Publication version: Published version
• Journal title: Farmaceutski glasnik
• Numbering: vol. 72, no. 11, pp. 747-760
• p-ISSN: 0014-8202
• URN:NBN: urn:nbn:hr:163:698895
• Publication: 2016
• Type of resource: Text
• Access conditions: Open access
• Created on: 2020-06-19 12:55:35