Fitokemijska karakterizacija bioaktivnih polifenolnih spojeva endemične vrste Centaurea ragusina L. (Asteraceae)

Scientific paper - Original scientific paper

• Author: Renata Jurišić Grubešić
• Author: Iva Domitrović
• Author: Mirko Ruščić
• Author: Jadranka Vuković Rodriguez
• Author: Dario Kremer
• Author's institution: University of Zagreb; Faculty of Pharmacy and Biochemistry; (Department of pharmaceutical analysis)
• Author's institution: University of Zagreb; Faculty of Pharmacy and Biochemistry; (Department of pharmaceutical botany)
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Pharmacy; Pharmacy

Abstract (english)

Phytochemical characterization of the Croatian endemic
species Centaurea ragusina L. (Asteraceae) was carried out. The presence
of polyphenols in above ground plant parts was proven by using chemical
reactions of developing colored products and precipitates. The thin layer
chromatography showed the presence of quercetin, rutin, and chlorogenic
acid in the methanolic extract of C. ragusina. Quantitative analysis of total
polyphenols (TP), tannins (T), fiavonoids (F), and phenolic acids (PA) was
carried out using three different spectrophotometric methods. The contents of
analyzed polyphenolic compounds were as follows: 3.04±0.04% (TP),
0.36±0.04% (T), 0.25±0.00% (F), and 0.38±0.01% (PA). This phytochemical
characterization is a contribution to the scientific study of Croatian
endemic species and completes the existing knowledge about phytotherapeutic
potential of C. ragusina, especially in relation to the content of
bioactive polyphenolic substances.

• Keywords (croatian): endemične biljke; dubrovačka zečina; Centaurea ragusina L. (Asteraceae); fitokemijska karakterizacija; polifenoli
• Language: croatian
• Publication type: Scientific paper - Original scientific paper
• Publication status: Published
• Peer review: Peer review - domestic
• Publication version: Published version
• Journal title: Farmaceutski glasnik
• Numbering: vol. 72, no. 9, pp. 569-584
• p-ISSN: 0014-8202
• URN:NBN: urn:nbn:hr:163:469218
• Publication: 2016
• Type of resource: Text
• Access conditions: Open access
• Created on: 2020-07-07 14:17:42