Antidepresivi

Professional paper - Professional paper

• Author: Zrinka Rajić
• Author's institution: University of Zagreb; Faculty of Pharmacy and Biochemistry; (Department of medicinal chemistry)
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Pharmacy; Pharmacy

Abstract (english)

Depression is a mental condition in which one feels exhausted, worthless, helpless,
hopeless and desperate. lt affects 10-12% population of the Western countries. With out
treatment, symptoms can last for weeks, rri.onths and years. Appropriate treatment
can help most people who suffer from depression. The antidepressant class of drugs are
well-known and widely used today. They are classified according to their principal mechanism
of action: selective norepinefrine reuptake inhibitors (SNRI), selective serotonin
reuptake inhibitors (SSRI), norepinefrine and serotonin reuptake inhibitors (NSRI),
dopamin and norepinefrine reuptake inhibitors (DNRI), serotonin receptor modulators
(SARI and NaSSA) and monoamine oxidase inhibitors (MAOI). New generations of antidepressants,
such as SSRis, have more favourable side effect and pharmacokinetic profiles
then the older generations of antidepressants, which has resulted in improved patient
compliance and therapeutic outcomes for patients with major depressive disorder.

• Keywords (croatian): antidepresivi; depresija; serotonin
• Language: croatian
• Publication type: Professional paper - Professional paper
• Publication status: Published
• Peer review: Peer review - domestic
• Publication version: Published version
• Journal title: Farmaceutski glasnik
• Numbering: vol. 66, no. 3, pp. 133-146
• p-ISSN: 0014-8202
• URN:NBN: urn:nbn:hr:163:516183
• Publication: 2010
• Type of resource: Text
• Access conditions: Open access
• Created on: 2020-09-25 13:02:18