Suhi ekstrakt plodova sikavice (Silybum marianum (L.) Gaertn.) - terapeutik jetre

Professional paper - Professional paper

• Author: Danica Kuštrak; MBZ: 126103
• Author's institution: University of Zagreb; Faculty of Pharmacy and Biochemistry; (Department of pharmacognosy)
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Pharmacy; Pharmacy

Abstract (english)

The milk thistle, Silybum marianum (L.) Gaertn. (= Carduus marianus
L.) belongs to the Asteraceae family. The history of this medicinal plant is
going back to· the time of the birth of Christ. It's fruits, Fructus Cardui Mariae,
commonly known as seeds, were formerly employed as a herbal remedy, while
nowdays they or their products in effective dosage are recognized as a therapeutic
agent. Wagner et al. (1968) were found in fruits of the milk thistle a group of flavonoid
compounds. These compounds were given the name silymarin. Further studies
showed that silymarin consists of three isomeric compounds: silibinin, silidianin
and silicristin (molecular formula: C,){,.0,., MW 482.45)
The positive effect of silymarin on elevated serum enzyme levels - an indication of
parenchymal damage in patients with chronic liver diseases -has been clearly apparent
in various nonblind controlled trials.
Indicatons of silymarin: toxic liver damage, for supportive treatment in chronic inflammatory
liver diseases and cirrhosis.

• Keywords (croatian): sikavica; Silybum marianum (L.) Gaertn.; silimarin; jetra; hepatoterapija
• Language: croatian
• Publication type: Professional paper - Professional paper
• Publication status: Published
• Peer review: Peer review - domestic
• Publication version: Published version
• Journal title: Farmaceutski glasnik
• Numbering: vol. 56, no. 6, pp. 183-187
• p-ISSN: 0014-8202
• URN:NBN: urn:nbn:hr:163:384237
• Publication: 2000
• Type of resource: Text
• Access conditions: Open access
• Created on: 2021-03-05 14:31:08