Beta-karbolini - u potrazi za novim terapijskim mogućnostima

Professional paper - Professional paper

• Author: Vedrana Konjevod
• Author: Zrinka Rajić
• Author: Ivana Perković
• Author's institution: University of Zagreb; Faculty of Pharmacy and Biochemistry; (Department of medicinal chemistry)
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Pharmacy; Pharmacy

Abstract (english)

Beta-carboline alkaloids, natural products ubiquitously distributed
in various plants and animals represent a pharmacologically
very attractive scaffold due to its convenient synthesis and structural diversity.
Their pharmacological potential has been known for centuries and a large number
of publications is focused on exploring the possibilities for their application.
To name a few, these compounds have exerted antimalarial, antineoplastic, anticonvulsant
and anxiolytic activity. In addition, several beta-carboline drugs are
already used in therapy or are currently in clinical trials.

• Keywords (croatian): beta-karbolini; alkaloidi; sintetski derivati
• Language: croatian
• Publication type: Professional paper - Professional paper
• Publication status: Published
• Peer review: Peer review - domestic
• Publication version: Published version
• Journal title: Farmaceutski glasnik
• Numbering: vol. 77, no. 5-6, pp. 275-285
• p-ISSN: 0014-8202
• URN:NBN: urn:nbn:hr:163:583993
• Publication: 2021
• Type of resource: Text
• Access conditions: Open access
• Created on: 2021-09-06 15:39:44