Određivanje ukupnih polifenola i antioksidativne aktivnosti dodataka prehrani koji sadrže soju

master's thesis

• Title (english): Determination of total polyphenol content and antioxidant activity of soy-based dietary supplements
• Author: Iva Brletić
• Mentor: Daniela Amidžić Klarić (mentor)
• Committee member: Daniela Amidžić Klarić (predsjednik povjerenstva)
• Committee member: Maja Friščić (član povjerenstva)
• Committee member: Hrvoje Rimac (član povjerenstva)
• Granter: University of Zagreb; Faculty of Pharmacy and Biochemistry; (Department of pharmaceutical analysis); Zagreb
• Defense date and country: 2021-07-23, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Pharmacy; Pharmacy

Abstract

Broj dodataka prehrani koji sadrže soju na tržištu i njihova uporaba u stalnom su porastu. Ova skupina dodataka prehrani postala je iznimno zanimljiva zbog preventivnog i terapijskog djelovanja na ljudsko zdravlje. Cilj ovog rada bio je procijeniti kvalitetu ispitivanih dodataka prehrani koji sadrže soju obzirom na ukupni sadržaj polifenola te odrediti antioksidativnu aktivnost istih. Analizirani dodaci prehrani koji sadrže soju mogu se smatrati dobrim izvorom polifenolnih sastavnica. Antioksidativna aktivnost ispitivanih dodataka prehrani u skladu je sa sadržajem ovih biološki aktivnih sastavnica. Korelacija između ukupnog sadržaja polifenola i antioksidativnog učinka snažno je statistički značajna, pa se može zaključiti da je antioksidativno djelovanje proporcionalno sadržaju ovih sekundarnih metabolita. HPLC-DPPH korištena metoda je brza i ponovljiva te prikladna za rutinsku analizu uzoraka. Rezultati ove studije doprinose boljem razumijevanju sadržaja ukupnih polifenola i antioksidativne aktivnosti dodataka prehrani koji sadrže soju.

Abstract (english)

The number of soy-based dietary supplements and their use is constantly increasing. This group of dietary supplements has become extremely interesting due to its preventive and therapeutic effects on human health. This study aimed to evaluate the quality of the tested soy-based dietary supplements concerning the total polyphenol content and their antioxidant activity. The analyzed soy-based dietary supplements could be considered a good source of polyphenolic constituents. The antioxidant activity of the tested dietary supplements is in accordance with the content of these biologically active compositions. The correlation between total polyphenol content and antioxidant activity is strongly statistically significant, so it could be concluded that antioxidant activity is proportionally contained in these secondary metabolisms. This HPLC-DPPH method is fast and reproducible, and suitable for use in routine analysis. The results of this study contribute to a better understanding of the content of total polyphenols and the antioxidant activities of soy-based dietary supplements.

• Keywords: polifenoli; antioksidativna aktivnost; dodaci prehrani; soja
• Keywords (english): polyphenols; antioxidant activity; dietary supplements; soy
• Language: croatian
• URN:NBN: urn:nbn:hr:163:180165
• Study programme: Title: Pharmacy; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access; Embargo expiration date: 2023-07-23
• Created on: 2022-02-28 10:02:45