Korijen mongolskog kozlinca u suvremenoj fitofarmaciji

master's thesis

• Title (english): Astragalus mongholicus root in modern phytopharmacy
• Author: Ana Jurelinac
• Mentor: Sanda Vladimir-Knežević (mentor)
• Committee member: Sanda Vladimir-Knežević (predsjednik povjerenstva)
• Committee member: Biljana Blažeković (član povjerenstva)
• Committee member: Renata Jurišić Grubešić (član povjerenstva)
• Granter: University of Zagreb; Faculty of Pharmacy and Biochemistry; (Department of pharmacognosy); Zagreb
• Defense date and country: 2020-09-29, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Pharmacy; Pharmacy

Abstract

Astragalus mongholicus B. stoljećima se primjenjuje u liječenju hepatitisa, kardiovaskularnih poremećaja, respiratornih infekcija, bubrežnih i kožnih bolesti te služi kao tonik, antidijabetik i diuretik. Polisaharidi, izoflavoni i triterpenski saponini smatraju se glavnim sastavnicama odgovornim za terapijske učinke korijena kozlinca koji se pripisuju njegovu imunomodulacijskom, protuupalnom i antioksidativnom djelovanju. Klinička ispitivanja ukazala su na potencijal primjene kozlinca u terapiji virusnog miokarditisa, ishemijskih bolesti srca, kronične bolesti bubrega, kongestivnog zatajenja srca i kroničnog virusnog hepatitisa. Novijim studijama ispituje se i njegova učinkovitost u liječenju leukopenije, karcinoma pluća, alergijskog rinitisa i prevenciji infekcija.

Abstract (english)

Astragalus mongholicus B. has been used for centuries to treat hepatitis, cardiovascular disorders, respiratory infections, kidney diseases, skin diseases and has been taken as a herbal tonic, antidiabetic and diuretic agent. Polysaccharides, isoflavones and triterpenoid saponins are considered to be the main active ingredients responsible for the therapeutic activity of Astragalus root, which is related to its immunomodulatory, anti-inflammatory and antioxidant properties. In conducted clinical trials Astragalus showed potential for treating viral myocarditis, ishemic heart diseases, chronic kidney disease, congestive heart failure and chronic hepatitis. Recent studies have focused on investigating its efficacy in the treatment of leukopenia, lung cancer, allergic rhinitis and prevention of infectious diseases.

• Keywords: mongolski kozlinac; korijen mongolskog kozlinca; Astragalus mongholicus; Astragalus membranaceus var. mongholicus; fitoterapija
• Keywords (english): Astragalus; Astragalus root; Astragalus mongholicus; Astragalus membranaceus var. mongholicus; phytotherapy
• Language: croatian
• URN:NBN: urn:nbn:hr:163:746356
• Study programme: Title: Pharmacy; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access; Embargo expiration date: 2022-09-29
• Created on: 2022-08-30 13:26:18