Akutne i kronične nuspojave kemoterapije i terapijske mogućnosti zbrinjavanja istih u pacijentica koje su preboljele rani rak dojke

master's thesis

• Title (english): Acute and chronic side effects of chemotherapy and therapeutic options for their management in patients who have survived early breast cancer
• Author: Marija Tomas
• Mentor: Iva Mucalo (mentor)
• Committee member: Iva Mucalo (predsjednik povjerenstva)
• Committee member: Tajana Silovski (član povjerenstva)
• Committee member: Andrea Brajković (član povjerenstva)
• Granter: University of Zagreb; Faculty of Pharmacy and Biochemistry; (Centre for applied pharmacy); Zagreb
• Defense date and country: 2023-07-20, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Pharmacy; Pharmacy

Abstract

Adjuvantna kemoterapija u liječenju karcinoma dojke ima raznovrsne mehanizme djelovanja te ne djeluje isključivo na tumor nego i na ostale dijelove tijela što rezultira različitim nuspojavama. Neke od najčešćih su mučnina, povraćanje, proljev, umor, gubitak kose, kognitivne promjene, neuropatija itd. Navedene nuspojave smanjuju kvalitetu života, kompliciraju ili prekidaju liječenje te ponekad ugrožavaju život samog pacijenta. Napredovanjem moderne medicine nuspojave koje prate liječenje se većinom mogu ublažiti nefarmakološkim mjerama, dodacima prehrani ili lijekovima. Uloga ljekarnika u zbrinjavanju onkoloških pacijenta postaje sve važnija. Ljekarnici su zdravstveni stručnjaci koji pacijentima mogu predložiti razne strategije ublažavanja nuspojava i odgovarajuću terapiju s ciljem poboljšanja njihove kvalitete života, lakšeg nastavka liječenja i posljedičnog smanjenja troškova u zdravstvu.

Abstract (english)

Adjuvant chemotherapy in the treatment of breast cancer has diverse mechanisms of action and does not only affect the tumor but also other parts of the body, resulting in various side effects. Some of the most common side effects include nausea, vomiting, diarrhea, fatigue, hair loss, cognitive changes, neuropathy, etc. These side effects reduce the quality of life, complicate or interrupt treatment, and sometimes jeopardize the patient's life. With the advancement of modern medicine, the side effects associated with treatment can mostly be alleviated through non-pharmacological measures, dietary supplements, or medications. The role of pharmacists is becoming increasingly important concerning oncology patients. With their knowledge, pharmacists can suggest strategies for mitigating side effects and provide appropriate therapy to improve their quality of life, facilitate the continuation of treatment, and simultaneously reduce healthcare costs.

• Keywords: rak dojke; kemoterapija; nuspojave kemoterapije; akutne nuspojave; kronične nuspojave
• Keywords (english): breast cancer; chemotherapy; chemotherapy side effects; acute side effects; chronic side effects
• Language: croatian
• URN:NBN: urn:nbn:hr:163:562719
• Study programme: Title: Pharmacy - integrated undergraduate and graduate - university study; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: sveučilišni magistar farmacije (sveučilišni magistar farmacije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-03-21 13:15:29