Ispitivanje adherentnosti pacijenata prilikom hospitalizacije

master's thesis

• Title (english): Measuring adherence at hospital admission
• Author: Emanuela Ljevar
• Mentor: Vesna Bačić Vrca (mentor)
• Committee member: Vesna Bačić Vrca (predsjednik povjerenstva)
• Committee member: Jelena Filipović-Grčić (član povjerenstva)
• Committee member: Sanda Vladimir-Knežević (član povjerenstva)
• Granter: University of Zagreb; Faculty of Pharmacy and Biochemistry; Zagreb
• Defense date and country: 2016-09-13, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Pharmacy; Pharmacy

Abstract

Adherencija prema propisanoj terapiji je primarna odrednica uspješnog liječenja. Loša adherencija
smanjuje optimalnu kliničku korist i tako smanjuje ukupnu učinkovitost zdravstvenog sustava.
Lijekovi neće biti učinkoviti ako pacijenti ne slijede propisanu terapiju. Adherencija u kroničnim
bolestima iznosi 50% u razvijenim zemljama. U zemljama u razvoju taj je postotak još niži.
Sposobnost pacijenta da prati svoj plan liječenja često je ugrožena sa više faktora poput
sociodemograskih čimbenika, karakteristika bolesti i propisane terapije.
Korišten je instrument za mjerenje koji se sastoji od dva dijela: prikupljanje sociodemografskih
podataka i originalna Morisky ljestvica za mjerenje adherencije sa osam pitanja.
U istraživanju je sudjelovalo 250 hospitaliziranih pacijenata u dobi 19-92 godina. Glavni izvor
podataka je bila medicinska dokumentacija bolesnika. Prosječna dob bila je 65 godina a svaki
pacijent je u prosjeku imao 5 komorbiditeta. Komorbiditeti, nuspojave, nedostatak znanja i
rehospitalizacija su neki od čimbenika koji utječu na stupanj adherencije. Približno polovica
ispitanika (37%) je pokazala lošu adherenciju. Ovim istraživanjem je pokazana da pacijenti na
dugotrajnim terapijama imaju nisku adherenciju.
Zdravstveni stručnjaci zajedno sa pacijentom i njihovim obiteljima trebaju biti stručni i odgovorni
u pridržavanju propisanoj terapiji.

Abstract (english)

Adherence to therapies is a primary determinant of treatment success. Poor adherence attenuates
optimum clinical benefits and therefore reduces the overall effectiveness of health systems.
Medicines will not be effective if patients do not follow prescribed treatment. Adherence to longterm
therapy for chronic illnesses in developed countries averages 50%. In developing countries,
the rates are even lower. The ability of patients to follow treatment plans in an optimal manner is
frequently compromised by more than one barrier, usually related to different aspects of the
problem. These include: the social and economic factors, the health care team/system, the
characteristics of the disease, disease therapies and patient-related factors. The instrument that was
used consisted of two parts: part one collects socio-demographic data, part two is the eight-item
original Morisky scale.
The study included 250 hospitalized patients aged 19-92 years. Information on adherence to
therapy was retrieved mainly from the patients medica! records. The average age of the patient was
found to be 65 years, and each patient bas an average 5 comorbidities. Comorbidities, side effects,
lack of knowledge and rehospitalization are factors that influencing adherence. Approximately half
of patients (3 7%) bave low adherence.
This study bas shown that patients on long-term therapy for chronic diseases have poor adherence.
Health professionals need to be trained in adherence and it is necessary that the patient, the family
and the community who support him or her all play an active role.

• Keywords: adherencija pacijenta; neadherencija pacijenta; kronične bolesti; komorbiditeti; rehospitalizacija; nuspojave lijekova
• Keywords (english): patient adherence; patient nonadherence; chronic diseases; comorbidities; rehospitalization; side effects of drugs
• Language: croatian
• URN:NBN: urn:nbn:hr:163:645396
• Study programme: Title: Pharmacy; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2016-11-28 16:52:37