Medicinska primjena opija od starih civilizacija do danas

master's thesis

• Title (english): Medicinal use of opium from old civilisations till today
• Author: Mihaela Rogić
• Mentor: Sanda Vladimir-Knežević (mentor)
• Committee member: Sanda Vladimir-Knežević (predsjednik povjerenstva)
• Committee member: Biljana Blažeković (član povjerenstva)
• Committee member: Živka Juričić (član povjerenstva)
• Granter: University of Zagreb; Faculty of Pharmacy and Biochemistry; (Department of pharmacognosy); Zagreb
• Defense date and country: 2016-09-30, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Pharmacy; Pharmacy

Abstract

Opijum je na zraku osušen mliječni sok koji curi iz zarezanih nezrelih tobolaca vrtnog maka, Papaver somniferum L. (Papaveracae). Poznato je da se vrtni mak koristio kao analgetik i sedativ najmanje tisuću godina prije Krista. Opijum sadrži veliki broj alkaloida, među kojima sljedeća četiri imaju širu medicinsku primjenu: morfin, kodein, papaverin, noskapin. Opijum se koristi kao sirovina za proizvodnju alkaloida, iako se oni danas mogu dobiti i direktnom ekstrakcijom iz tobolaca. Morfin je glavni alkaloid opija (10-20%). Primjenjuje se kao vrlo učinkovit analgetik, ali je klasificiran i kao narkotik. Opij je narkotična droga koja izaziva jaku ovisnost i služi za ilegalno dobivanje heroina.

Abstract (english)

Opium is air-dried latex obtained by incision from the unripe capsules of Papaver somniferum L (Papaveracae). The opium poppy was known as an analgesic and sedative more than a thousand years BC. Opium containes a large number of alkaloids. Four of them have attained wide medicinal use: morphine, codeine, papaverine and noscapine. Opium is used as a raw material for preparing alkaloids which can be also produced by direct extraction from the capsules. Morphine is the main alkaloid of opium (10-20%). It is used as a very effective analgesic, but it is classified as a narcotic. Opium is a highly addictive narcotic drug which is used for production of heroin.

• Keywords: Papaver somniferum; opij; alkaloidi; morfin
• Keywords (english): Papaver somniferum; opium; alkaloids; morphine
• Language: croatian
• URN:NBN: urn:nbn:hr:163:343641
• Study programme: Title: Pharmacy; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to students and staff of home institution
• Created on: 2017-09-14 10:10:32