Nove terapijske mogućnosti u liječenju psorijaze

master's thesis

• Title (english): New therapeutic possibilities in psoriasis treatment
• Author: Klara Šimić
• Mentor: Petra Turčić (mentor)
• Committee member: Petra Turčić (predsjednik povjerenstva)
• Committee member: Renata Jurišić Grubešić (član povjerenstva)
• Committee member: Ivan Pepić (član povjerenstva)
• Granter: University of Zagreb; Faculty of Pharmacy and Biochemistry; (Department of pharmacology); Zagreb
• Defense date and country: 2017-06-06, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Pharmacy; Pharmacy

Abstract

Nove terapijske mogućnosti u liječenju psorijaze predstavalju velik napredak za znanost i društvo općenito. Budući da je to još uvijek nedovoljno istraženo područje, velik broj lijekova koji predstavljaju novitete u liječenju psorijaze još uvijek nije odobren niti dovoljno istražen. Zahvaljujući tome, puno je mjesta za unaprjeđenje i istraživanje lijekova u ovom smjeru. S obzirom da je psorijaza bolest u kojoj se odvijaju slični procesi kao u drugim autoimunosnim bolestima, otkrivanje i istraživanje novih terapijskih mogućnosti bilo bi korisno i za ostale bolesti slične etiologije. Razvojem novih lijekova mogle bi se ublažiti ili izbjeći nuspojave, pojednostaviti primjena i postići bolji rezultati liječenja. Od novih lijekova za liječenje psorijaze na hrvatskom tržištu trenutno se nalazi 5 lijekova. Prije nego postanu kandidati za primjenu novih lijekova, bolesnici trebaju proći selekcijski postupak. U Hrvatskoj otprilike 0,735% oboljelih od psorijaze prima biološku terapiju. Kako bi se taj postotak povisio, treba raditi na unaprjeđenju znanosti i podizanju svjesti građana. Farmaceut, kao dio zdravstvenog tima, može doprinijeti i unaprjeđenju znanosti i podizanju svjesti o psorijazi.

Abstract (english)

New therapeutic possibilities in psoriasis treatment represent a huge progress in science af well as for the whole society. Since this area is still insufficirntly researched, huge number of novel medicines are not approved or even researched enought. Therefore, in this area exist a big room for improvement and for medicines research. Psoriasis is a disease that is followed by similar processes visible in other autoimmune diseases, therefore new treatment options would benefit to other diseases with similar etiology. Development of new drugs would enable mitigation or avoidance of side effects, simplification of medicine application and achieving better treatment results. On Croatian market, five new psoriasis medicines are available. Before becoming candidates for new medicines application, patients have to go trough a selection process. Biological therapy is given to approximately 0,735% psoriasis patients. In order to increase that percentage, it is needed to work on science improvement as well as raising people’s awareness. Pharmacist, as part of health care team, can contribute to that.

• Keywords: psorijaza; biološki lijekovi; male molekule
• Keywords (english): psoriasis; biologic agents; small molecules
• Language: croatian
• URN:NBN: urn:nbn:hr:163:421271
• Study programme: Title: Pharmacy; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2017-11-17 14:55:05