Stavovi i uvjerenja pacijenata na terapiji antidepresivima, inhalacijskim kortikosteroidima i statinima

master's thesis

• Title (english): Attitudes and beliefs of patients on their therapy with antidepressants, inhaled corticosteroids and statins
• Author: Andrea Jarak
• Mentor: Maja Ortner Hadžiabdić (mentor)
• Committee member: Maja Ortner Hadžiabdić (predsjednik povjerenstva)
• Committee member: Lidija Bach-Rojecky (član povjerenstva)
• Committee member: Miranda Sertić (član povjerenstva)
• Granter: University of Zagreb; Faculty of Pharmacy and Biochemistry; (Centre for applied pharmacy); Zagreb
• Defense date and country: 2019-07-18, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Pharmacy; Pharmacy

Abstract

Cilj ovog diplomskog rada bio je istražiti stavove i uvjerenja pacijenata o njihovoj terapiji antidepresivima, statinima,
inhalacijskim kortikosteroidima u terapiji astme i terapiji lijekovima općenito. U tu svrhu korišteni su BMQ upitnik,
MMAS-4 skala, obrazac za prikupljanje medikacijske povijesti te obrazac za provjeru pacijentovog razumijevanja
indikacije, učinkovitosti i sigurnosti terapije. Također su prikupljeni opći i demografski podaci ispitanika. U istraživanje
su bili uključeni punoljetni pacijenti koji troše lijekove iz skupine antidepresiva, statina i inhalacijskih kortikosteroida u
kroničnoj terapiji (duže od 3 mjeseca). Ovo istraživanje je provedeno kao presječno, opažajno (opservacijsko).
Ispitivanje se provodilo u javnim ljekarnama, u Klinici za psihijatriju Vrapče te u Poliklinici za bolesti dišnog sustava
na području grada Zagreba. U ispitivanju je sudjelovalo 290 pacijenata; 93 ispitanika je uzimalo antidepresive, 97 ih je
koristilo inhalacijske kortikosteroide, a 100 pacijenata lijekove iz skupine statina.
Rezultati su pokazali da ispitanici s višim stupnjem obrazovanja smatraju lijekove manje štetnima od onih s nižim
stupnjem obrazovanja. Ispitanici koji žive u bračnoj zajednici su lijekove smatrali štetnijima od ispitanika koji nisu u
braku. Nezaposleni pacijenti su najviše smatrali kako su lijekovi štetni, zatim slijede umirovljenici i oni zaposleni, dok
studenti većinom nisu vjerovali u štetnost lijekova. Nezaposleni ispitanici najmanje vjeruju u dobrobit lijekova, dok
studenti najviše. Za razliku od ostalih, nezaposleni ispitanici značajnije su bili zabrinuti za svoju antidepresivnu terapiju.
Oženjeni/udani pacijenti na inhalacijskim kortikosteroidima su pokazali veću adherenciju od neoženjenih/neudanih, a
umirovljenici veću od studenata i onih nezaposlenih. Većina ispitanika je pokazala dobru adherenciju, no zaključeno je
kako su pacijenti na terapiji statinima adherentniji od pacijenata na terapiji antidepresivima i inhalacijskim
kortikosteroidima. Kvalitativni dio upitnika pokazao je da pacijenti koji uzimaju inhalacijske kortikosteroide i statine
većinom ne percipiraju postojanje terapijskih problema. Pacijenti koji uzimaju antidepresive usprkos činjenici da su
iskusili najveći broj nuspojava (35,5 %) većinom razumiju razlog njihovog uzimanja i smatraju ih učinkovitima.

Abstract (english)

The aim of this graduate thesis was to explore the attitudes and beliefs of patients on their therapy with antidepressants,
statins, inhaled corticosteroids in asthma therapy and drug therapy in general. We used BMQ questionnaire, Morisky
Medication-Taking Adherence Scale-MMAS (4-item), Patient Medication History Form and form for checking the
indication, efficacy and safety. We also gathered general and demographic patient data. The study included adult
patients who used antidepressant drugs, statins and inhaled corticosteroids during chronic therapy (longer than 3 months)
and who understood the Croatian language. This research was conducted as a cross-section, observational research. The
trial was conducted in community pharmacies, within the Vrapče hospital and at the Polyclinic for respiratory diseases
in Zagreb. 290 patients participated in the study; 93 patients were taking antidepressants, 97 were using inhaled
corticosteroids and 100 patients were taking statin drugs.
The results have shown that respondents with higher education considered drugs less harmful than those with a lower
level of education. Married patients considered the drugs to be more harmful than unmarried ones. Unemployed patients
had stronger beliefs that the drugs were harmful, followed by the retired and the employed ones, while the students
mostly didn’t share the belief on drugs being harmful. Furthermore, unemployed respondents least believe in the benefits
of medication, while students the most. Unemployed respondents were mostly worried about their antidepressant
therapy. Married patients who took inhaled corticosteroids showed greater adherence than unmarried ones and retirees
showed greater adherence than students and those unemployed. Most patients showed good adherence, but it was
concluded that patients with statin therapy are more adherent than patients with antidepressant and inhaled corticosteroid
therapy. The qualitative part of the questionnaire showed that patients taking inhaled corticosteroids and statins mostly
do not perceive the existence of therapeutic problems. Patients taking antidepressants although experienced the highest
percentage of side effects (35.5%) mostly know why they are taking their medication and they consider them to be
effective.

• Keywords: antidepresivi; inhalacijski kortikosteroidi; statini; adherencija; BMQ
• Keywords (english): antidepressants; inhaled corticosteroids; statins; adherence; BMQ
• Language: croatian
• URN:NBN: urn:nbn:hr:163:994248
• Study programme: Title: Pharmacy; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2020-02-21 15:28:13