prikaz prve stranice dokumenta Filaggrin and atopic march
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Filaggrin and atopic march
Biochemia Medica, 29 (2019), 2; 214-227. https://doi.org/10.11613/BM.2019.020501
Čepelak, Ivana; Dodig, Slavica; Pavić, Ivan

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Čepelak, I., Dodig, S. & Pavić, I. (2019). Filaggrin and atopic march. Biochemia Medica, 29. (2), 214-227. doi: 10.11613/BM.2019.020501

Čepelak, Ivana, et al. "Filaggrin and atopic march." Biochemia Medica, vol. 29, no. 2, 2019, pp. 214-227. https://doi.org/10.11613/BM.2019.020501

Čepelak, Ivana, Slavica Dodig and Ivan Pavić. "Filaggrin and atopic march." Biochemia Medica 29, no. 2 (2019): 214-227. https://doi.org/10.11613/BM.2019.020501

Čepelak, I., Dodig, S. and Pavić, I. (2019) 'Filaggrin and atopic march', Biochemia Medica, 29(2), pp. 214-227. doi: 10.11613/BM.2019.020501

Čepelak I, Dodig S, Pavić I. Filaggrin and atopic march. Biochemia Medica [Internet]. 2019 [cited 2024 April 21];29(2):214-227. doi: 10.11613/BM.2019.020501

I. Čepelak, S. Dodig and I. Pavić, "Filaggrin and atopic march", Biochemia Medica, vol. 29, no. 2, pp. 214-227, 2019. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:163:831297. [Accessed: 21 April 2024]

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Metadata
Title (english)Filaggrin and atopic march
AuthorIvana Čepelak
AuthorSlavica Dodig
AuthorIvan Pavić
Author's institutionUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of medical biochemistry and haematology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Medical Biochemistry
Abstract (english)
There is an increasing number of experimental, genetic and clinical evidence of atopic dermatitis expression as a pre-condition for later development of other atopic diseases such as asthma, food allergy and allergic rhinitis. Atopic dermatitis is a heterogeneous, recurrent childhood disease, also present in the adult age. It is increasingly attributed to systemic features and is characterized by immunological and skin barrier integrity and function dysregulation. To maintain the protective function of the skin barrier, in particular the maintenance of pH, hydration and antimicrobial functions, the filaggrin, among others, plays a significant role. Filaggrin is a multifunctional, histidine-rich, insoluble protein. The lack of filaggrin is associated with various cutaneous (e.g. ichthyosis vulgaris, allergic contact dermatitis) and non-cutaneous (e.g. diabetes, inflammatory conditions of the gastrointestinal tract) diseases and may be a result of genetic, immunological factors combined with environmental factors. In this review we summarised (emphasized) recent findings in understanding the role of filaggrin in atopic dermatitis and other diseases, participants in the atopic march.
Keywords (english)
Languageenglish
Publication typeOther - Other
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleBiochemia Medica
Numberingvol. 29, no. 2, pp. 214-227
p-ISSN1330-0962
e-ISSN1846-7482
DOIhttps://doi.org/10.11613/BM.2019.020501
URN:NBNurn:nbn:hr:163:831297
Publication2019
Document URLhttps://hrcak.srce.hr/221073
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-04-09 14:47:45