A QSAR study of 3-(phthalimido alkyl)-pyrazolin-5-ones

Nikolić, Sonja; Medić-Šarić, Marica; Matijević-Sosa, Julija

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Scientific paper - Conference paper

A QSAR study of 3-(phthalimido alkyl)-pyrazolin-5-ones

Croatica Chemica Acta, 66 (1993), 1; 151-160. urn:nbn:hr:163:950602

Nikolić, Sonja; Medić-Šarić, Marica; Matijević-Sosa, Julija

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APA 6th Edition

Nikolić, S., Medić Šarić, M. & Matijević Sosa, J. (1993). A QSAR study of 3-(phthalimido alkyl)-pyrazolin-5-ones. Croatica Chemica Acta, 66. (1), 151-160. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:950602

MLA 8th Edition

Nikolić, Sonja, et al. "A QSAR study of 3-(phthalimido alkyl)-pyrazolin-5-ones." Croatica Chemica Acta, vol. 66, no. 1, 1993, pp. 151-160. https://urn.nsk.hr/urn:nbn:hr:163:950602

Chicago 17th Edition

Nikolić, Sonja, Marica Medić Šarić and Julija Matijević Sosa. "A QSAR study of 3-(phthalimido alkyl)-pyrazolin-5-ones." Croatica Chemica Acta 66, no. 1 (1993): 151-160. https://urn.nsk.hr/urn:nbn:hr:163:950602

Harvard

Nikolić, S., Medić Šarić, M. and Matijević Sosa, J. (1993) 'A QSAR study of 3-(phthalimido alkyl)-pyrazolin-5-ones', Croatica Chemica Acta, 66(1), pp. 151-160. Available at: https://urn.nsk.hr/urn:nbn:hr:163:950602 (Accessed 12 November 2024)

Vancouver

Nikolić S, Medić Šarić M, Matijević Sosa J. A QSAR study of 3-(phthalimido alkyl)-pyrazolin-5-ones. Croatica Chemica Acta [Internet]. 1993 [cited 2024 November 12];66(1):151-160. Available at: https://urn.nsk.hr/urn:nbn:hr:163:950602

IEEE

S. Nikolić, M. Medić Šarić and J. Matijević Sosa, "A QSAR study of 3-(phthalimido alkyl)-pyrazolin-5-ones", Croatica Chemica Acta, vol. 66, no. 1, pp. 151-160, 1993. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:163:950602. [Accessed: 12 November 2024]

Cite this item: https://urn.nsk.hr/urn:nbn:hr:163:950602

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Title (english)	A QSAR study of 3-(phthalimido alkyl)-pyrazolin-5-ones
Author	Sonja Nikolić
Author	Marica Medić-Šarić
Author	Julija Matijević-Sosa
Author's institution	University of Zagreb Faculty of Pharmacy and Biochemistry (Department of biochemistry and molecular biology)
Author's institution	University of Zagreb Faculty of Pharmacy and Biochemistry (Department of medicinal chemistry)
Scientific / art field, discipline and subdiscipline	BIOMEDICINE AND HEALTHCARE Pharmacy Pharmacy
Abstract (english)	A group of 17 new 3-(phthalimidoalkyl)-pyrazolin-5-ones were tested for their mitodepressive activity upon the growth of Lepidium sativum L. seeds (Cresson). All of them have shown mitodepressive effect on the growth of the plant. Four topological indices (the Wiener index, the valence-connectivity index, the Balaban index and the information-theoretic index) were used in QSAR studies (inhibition of plant growth in % and cytostatic activity in ED50) on these compounds. We obtained QSAR models that can predict cytostatic activity on the HeLa cells (in ED50) with considerable accuracy.
Language	english
Publication type	Scientific paper - Conference paper
Publication status	Published
Peer review	Peer review - international
Publication version	Published version
Journal title	Croatica Chemica Acta
Numbering	vol. 66, no. 1, pp. 151-160
p-ISSN	0011-1643
e-ISSN	1334-417X
URN:NBN	urn:nbn:hr:163:950602
Publication	1993
Document URL	https://hrcak.srce.hr/137101
Type of resource	Text
Access conditions	Open access
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Created on	2020-04-29 15:09:36