Secondary a-deuterium isotope effects in the reaction of 2-phenylethyltrimethylammonium ion by hydroxide ion in aqueous solution and by ethoxide ion in ethanol

Scientific paper - Original scientific paper

• Author: S. Ašperger
• Author: L. Klasinc
• Author: D. Pavlović
• Author's institution: University of Zagreb; Faculty of Pharmacy and Biochemistry
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Chemistry

Abstract (english)

Secondary a-deuterium isotope effects in the reaction of
2-phenylethyltrimethylammonium iodide with hydroxide ion in
aqueous solution at 97.0° and with ethoxide ion in ethanol at 40.0°
have been found to be very small. The results .suggest that the
hydrogen compound reacts slightly faster than the deuterium
compound. The secondary a-deuterium isotope effect in the reaction
of 2-phenylethyl bromide with sodium ethoxide in ethanol is
appreciably larger and ammounts to 9 per cent per deuterium
atom at 59.8°. The mechanistic implications of these results are
discussed.

• Language: english
• Publication type: Scientific paper - Original scientific paper
• Publication status: Published
• Peer review: Peer review - international
• Publication version: Published version
• Journal title: Croatica Chemica Acta
• Numbering: vol. 36, no. 3, pp. 159-163
• p-ISSN: 0011-1643
• e-ISSN: 1334-417X
• URN:NBN: urn:nbn:hr:163:798691
• Publication: 1964
• Document URL: https://hrcak.srce.hr/208304
• Type of resource: Text
• Access conditions: Open access
• Created on: 2020-05-11 14:26:50