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Professional paper - Review paper
Nanokristali djelatne tvari: fizičko-kemijska, farmaceutsko-tehnološka, biofarmaceutska i terapijska svojstva
Farmaceutski glasnik, 71 (2015), 7-8; 355-384. urn:nbn:hr:163:912337
Lovrić, Jasmina; Hafner, Anita; Radiković, Maja; Juretić, Marina; Duerrigl, Marjana; Perina Lakoš, Gordana; Pepić, Ivan

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Lovrić, J., Hafner, A., Radiković, M., Juretić, M., Duerrigl, M., Perina Lakoš, G. & Pepić, I. (2015). Nanokristali djelatne tvari: fizičko-kemijska, farmaceutsko-tehnološka, biofarmaceutska i terapijska svojstva. Farmaceutski glasnik, 71. (7-8), 355-384. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:912337

Lovrić, Jasmina, et al. "Nanokristali djelatne tvari: fizičko-kemijska, farmaceutsko-tehnološka, biofarmaceutska i terapijska svojstva." Farmaceutski glasnik, vol. 71, no. 7-8, 2015, pp. 355-384. https://urn.nsk.hr/urn:nbn:hr:163:912337

Lovrić, Jasmina, Anita Hafner, Maja Radiković, Marina Juretić, Marjana Duerrigl, Gordana Perina Lakoš and Ivan Pepić. "Nanokristali djelatne tvari: fizičko-kemijska, farmaceutsko-tehnološka, biofarmaceutska i terapijska svojstva." Farmaceutski glasnik 71, no. 7-8 (2015): 355-384. https://urn.nsk.hr/urn:nbn:hr:163:912337

Lovrić, J., et al. (2015) 'Nanokristali djelatne tvari: fizičko-kemijska, farmaceutsko-tehnološka, biofarmaceutska i terapijska svojstva', Farmaceutski glasnik, 71(7-8), pp. 355-384. Available at: https://urn.nsk.hr/urn:nbn:hr:163:912337 (Accessed 20 April 2024)

Lovrić J, Hafner A, Radiković M, Juretić M, Duerrigl M, Perina Lakoš G, and sur.. Nanokristali djelatne tvari: fizičko-kemijska, farmaceutsko-tehnološka, biofarmaceutska i terapijska svojstva. Farmaceutski glasnik [Internet]. 2015 [cited 2024 April 20];71(7-8):355-384. Available at: https://urn.nsk.hr/urn:nbn:hr:163:912337

J. Lovrić, et al., "Nanokristali djelatne tvari: fizičko-kemijska, farmaceutsko-tehnološka, biofarmaceutska i terapijska svojstva", Farmaceutski glasnik, vol. 71, no. 7-8, pp. 355-384, 2015. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:163:912337. [Accessed: 20 April 2024]

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Title (croatian)Nanokristali djelatne tvari: fizičko-kemijska, farmaceutsko-tehnološka, biofarmaceutska i terapijska svojstva
AuthorJasmina Lovrić
AuthorAnita Hafner
AuthorMaja Radiković
AuthorMarina Juretić
AuthorMarjana Duerrigl
AuthorGordana Perina Lakoš
AuthorIvan Pepić
Author's institutionUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of pharmaceutical technology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract (english)
Nanosizing is one of the most important drug delivery platform approaches for the commercial development of poorly soluble drug molecules. Reducing the particle size of the drug to a nano-scale leads to an increased surface area-to-volume ratio, increased dissolution velocity and adhesiveness, and improved in vivo performance of poorly soluble drugs. The commercialized large scale productions of drug nanocrystals such as top down (NanoCrystal", Dissocubes", Nanopure") and combination (NanoEdge"', smarcCrystal") technologies are presented and discussed. The unique physicochemical and biopharmaceucical properties of drug nanocrystals ensure a wide variety of their therapeutic applications. Drug nanocrystals formulated into convenient pharmaceutical dosage forms are suitable for oral, parenteral, pulmonary, dermal and ocular administration. Thus far, 3 oral nanocrystal medicinal product and 2 parenteral nanocrystal medicinal product are available for therapeutic use in the European Union.
Keywords (croatian)
Languagecroatian
Publication typeProfessional paper - Review paper
Publication statusPublished
Peer reviewPeer review - domestic
Publication versionPublished version
Journal titleFarmaceutski glasnik
Numberingvol. 71, no. 7-8, pp. 355-384
p-ISSN0014-8202
URN:NBNurn:nbn:hr:163:912337
Publication2015
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2020-10-01 12:08:44