Štetni učinci sunčevog ultraljubičastog zračenja

Professional paper - Professional paper

• Author: Ivan Pepić
• Author's institution: University of Zagreb; Faculty of Pharmacy and Biochemistry; (Department of pharmaceutical technology)
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Pharmacy; Pharmacy

Abstract (english)

Sunlight consists of radiation with differing wavelenght: infrared (IR), visible (VIS),
and ultraviolet (UV) radiation. Concerning skin damages and sun protection, the
UV-radiation is important. UV-radiation that reaches the earth consists of short wavelenght
UVC (< 280 nm), intermediate wavelength UVB (280- 320 nm) and long wavelength
UVA (320-400 nm). Under physiological conditions, human cells are exclusively
exposed to UVB and UVA radiation, because the ozone layer in the stratosphere
completely absorbs wavelengths < 290 nm. The amount of UVA radiation reaching
the earth's surface is approximately 20 times greater than that of UVB radiation.
Sun exposure induces acute and chronic effects on the skin depending on the wavelength
of radiation. UVB are mostly absorbed by the epidermis while UVA penetrate more significantly in the dermis. Acute UVB deleterious effects are sunburn and related
inflammation. Acute UVA exposure is mainly responsible for photoallergic and
phototoxic reactions. Chronic effects of UVB and UVA exposure include photoaging,
immunosupression and photocarcinogenesis. Apart from the skin, the organ most
susceptible to sunlight induced damage is the eye. Scientific evidence accumulates to
indicate that acute exposure to artificial light or chronic exposures to sunlight either
causes or exacerbates age-related ocular diseases. The adequate sunglasses provide
protection against ocular effects from sunlight exposure. The regular and adequate
use of sunscreenes, avoiding the sun around mid-day, staying in the shade, wearing
hats with brims which can shade the head, face and neck, and wearing clothes made
from tightly woven fabrics, are ali important factors that could prevent the deleterious
effects of sunlight. The mismatch between the expected protection achieved by
sunscreens and that observed in practice depends upon a number of factors .

• Keywords (croatian): sunčevo zračenje; ultraljubičasto zračenje; fotostarenje kože; fotokarcinogeneza; fotoimunosupresija
• Language: croatian
• Publication type: Professional paper - Professional paper
• Publication status: Published
• Peer review: Peer review - domestic
• Publication version: Published version
• Journal title: Farmaceutski glasnik
• Numbering: vol. 59, no. 6, pp. 235-247
• p-ISSN: 0014-8202
• URN:NBN: urn:nbn:hr:163:030933
• Publication: 2003
• Type of resource: Text
• Access conditions: Open access
• Created on: 2021-02-17 13:32:12