Elektronička cigareta - toksičnost, sigurnost i mogući rizici za zdravlje

master's thesis

• Title (english): Electronic cigarette - toxicity, safety and possible health risks
• Author: Toni Rogulj
• Mentor: Irena Žuntar (mentor)
• Committee member: Irena Žuntar
• Committee member: Suzana Inić
• Committee member: Jasna Jablan
• Granter: University of Zagreb; Faculty of Pharmacy and Biochemistry; Zagreb
• Defense date and country: 2015-09-29, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Pharmacy; Pharmacy

Abstract

Elektroničke cigarete (e-cigarete) su elektronički uređaji koji stvaraju aerosol nalik dimu koji korisnik udiše prilikom njihova korištenja. Taj dim obično sadrži nikotin ali ne i većinu drugih toksina koje pušači udišu konzumiranjem duhanske cigarete. E-cigarete su postale popularne među pušačima koji žele smanjiti rizik povezan s pušenjem. Ovaj diplomski rad napravljen je s ciljem da se prikupe rezultati kliničkih studija kako bi se analiziralo mogu li e-cigarete pomoći pušačima da prestanu pušiti ili da smanje pušenje, i jesu li e-cigarete sigurne kad se koriste u tu svrhu. Kontrolirani pokusi koji su dosad provedeni na ljudima daju ograničene dokaze koji pokazuju da neke vrste e-cigareta (one vrste koje su u tim pokusima istražene) mogu biti djelotvorne za prestanak pušenja i smanjenje količine popušenih cigareta. Međutim, još uvijek nema odgovarajućih dokaza koji bi pokazali koliko su e-cigarete djelotvornije u odnosu na druge metode koje se koriste za prestanak pušenja. Također postoje ograničeni podatci o sigurnosti e-cigareta jer je takvih proizvoda na tržištu mnogo, a samo mali broj tih uređaja ispitan je u kliničkim pokusima. Stoga se može reći da postoji mnogo otvorenih pitanja vezanih za djelotvornost za e-cigareta u usporedbi s drugim metodama za prestanak pušenja, a isto tako i za njihovu sigurnost. E-cigarete su još uvijek relativna novost i ne postoje dugoročne studije o njihovu utjecaju na zdravlje. U skladu s tim, Svjetska zdravstvena organizacija (WHO) preporučila je da se e-cigarete ne koriste
dok se ne utvrdi njihova potpuna sigurnost za zdravlje.

Abstract (english)

An electronic cigarette (e-cigarette) is an electronic device that creates smoke-like aerosol inhaled by user. This aerosol (vapor) containes nicotine but does not contain most of other toxins found in nicotine cigarettes. E-cigarettes became popular among smokers who want to decrease smoking related health risks. The aim of this diplomma thesis was to collect and analyze results of clinical studies on safety and efficacy of e-cigarettes. So far, controlled experiments on humans came with limited evidence showing that tested types of e-cigarettes can be efficient for smoking cessation and for decreasing daily amount of smoked cigarettes. Still, there is no relevant evidence on e-cigarette efficacy compared to conventional smoking cessation methods. Also, there is limited data on safety of e-cigarette since only small portion of available devices has been clinically tested. Hence, lots of questions are still to be answered regarding safety of e-cigarette usage and its
efficacy compared to other smoking cessation methods. E-cigarette is relatively new option for smokers (and non-smokers) so there are no studies on their long-term effects on human health. Based on that, World Health Organisation recommends not to use e-cigarettes untill their safety is tested and approved.

• Keywords: elektronička cigareta; e-cigareta; e-tekućina; parenje; toksičnost
• Keywords (english): electronic cigarette; e-cigarette; e-liquid; vaping; toxicity
• Language: croatian
• URN:NBN: urn:nbn:hr:163:186614
• Study programme: Title: Pharmacy; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to students and staff of home institution
• Created on: 2016-02-25 10:20:25