| Abstract | Cilj istraživanja: Cilj ovog rada bio je utvrditi terapijske probleme u bolesnika s bolestima pluća koji se
liječe u Klinici za plućne bolesti Jordanovac. Ispitanici i metode: Istraživanje je provedeno u Klinici za
plućne bolesti Jordanovac u razdoblju od studenog 2019. do veljače 2020. Intervjuiranjem bolesnika
ispunjen je obrazac za prikupljanje medikacijske povijesti i Sažeti upitnik o lijekovima za procjenu
adherencije. Prikupljeni podatci uključivali su osnovne podatke o bolesniku, povijest bolesti, propisane
lijekove prije hospitalizacije, laboratorijske pretrage te identificirane terapijske probleme. Alat za definiranje
terapijskih problema preuzet je od Cipolle i sur. (2012). Određena je učestalost pojedinih terapijskih
problema. Rezultati: U istraživanje je uključeno 57 ispitanika. Medijan dobi ispitanika bio je 67 godina, a
raspon od 22 do 90 godina. Prosječan broj dijagnoza iznosio je 8,65 ± 3,68, a kretao se u rasponu od 2 do
16. Prosječna vrijednost broja receptnih lijekova koje su ispitanici imali u terapiji iznosila je 8,68 ± 5,00
(raspon 1-20). Ukupno je identificirano 407 terapijskih problema, a svaki bolesnik je imao barem jedan
problem vezan uz terapiju. Broj terapijskih problema po osobi iznosio je 6,37 ± 3,77. Najviše ispitanika
(n=10; 17,5%) imalo je 3 terapijska problema u svojoj terapiji, a kod jednog ispitanika identificirano je čak
17 terapijskih problema. Najviše terapijskih problema utvrđeno je u skupini koja se odnosi na sigurnost
(n=143; 35.1%), zatim na indikaciju (n =124; 30.5%) pa učinkovitost (n = 88; 21,6%), i na kraju, adherenciju
(n=52; 12,8%). Zaključak: Rezultati ovog istraživanja ukazuju na značajnu ulogu ljekarnika koji svojim
kompetencijama mogu pridonijeti optimizaciji terapije bolesnika s plućnim bolestima, koristeći pri tom
strukturirani proces utvrđivanja terapijskih problema. Važno je nastaviti provoditi istraživanja koja će
dokumentirati učestalost terapijskih problema među svim skupinama bolesnika kao i poticati ljekarničke
intervencije u svrhu poboljšanja kliničkih ishoda i povećanja zadovoljstva bolesnika i zdravstvenih
djelatnika, ali i smanjenja troškova u zdravstvu. |
| Abstract (english) | Objectives: The aim of this study was to describe drug therapy problems in a cohort of patients with pulmonary
diseases treated at the Clinical Center for Pulmonary Diseases Jordanovac, University Hospital Centre Zagreb.
Subjects and methods: The study was conducted at the Clinical Center for Pulmonary Diseases Jordanovac in
the period from November 2019 to February 2020. By patient interviews, a form for collecting medication history
and the Brief Medication Questionnaire (BMQ) were completed. The collected data included basic patient
information, history of illness, prescribed medications prior to hospitalization, laboratory tests and identified
drug related problems. Drug related problems were evaluated according to categories presented by Cipolle et al.
(2012). Results: 57 patients were included in the research. The median age of the subjects was 67 years (range
22-90). The average number of diagnoses was 8.65 ± 3.68, ranging from 2 to 16. The average number of
prescription drugs in patient's therapy was 8.68 ± 5.00 (range 1-20). A total of 407 drug related problems were
identified, and each patient had at least one drug related problem. The number of drug related problems per
person was 6.37 ± 3.77. Most subjects (N=10; 17.5%) had 3 drug related problems in their therapy, and one
subject had 17 drug related problems. Most drug related problems were found in the group related to safety
(N=143; 35.1%), followed by indication (N=124; 30.5%), effectiveness (N=88; 21.6%), and finally, adherence
(N=52; 12.8%). Conclusion: The results of this research indicate a significant role of pharmacists who can
contribute to the therapy optimization of patients with pulmonary diseases, using a structured process of
identifying therapeutic problems. It is important to continue conducting research that will document frequency
of drug therapy problems among all groups of patients as well as encourage interventions to improve clinical
outcomes and increase patient and healthcare professional satisfaction, but also reduce healthcare costs. |
