Utvrđivanje terapijskih problema tijekom Stručnog osposobljavanja za ljekarnike u pacijenata koji u terapiji imaju lijek za liječenje boli

master's thesis

• Title (english): Drug related problems in patients taking analgesics identifed during pre-registration training for pharmacists
• Author: Marija Šain
• Mentor: Maja Ortner Hadžiabdić (mentor)
• Committee member: Maja Ortner Hadžiabdić (predsjednik povjerenstva)
• Committee member: Lidija Bach-Rojecky (član povjerenstva)
• Committee member: Miranda Sertić (član povjerenstva)
• Granter: University of Zagreb; Faculty of Pharmacy and Biochemistry; (Centre for applied pharmacy); Zagreb
• Defense date and country: 2021-09-19, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Pharmacy; Pharmacy

Abstract

Cilj istraživanja: Primarni cilj ovog rada bio je utvrditi terapijske probleme prisutne kod pacijenata koji u
terapiji imaju analgetik. Sekundarni cilj rada bio je ispitati uspješnost prepoznavanja problema od strane
studenata farmacije. Ispitanici i metode: studenti pete godine farmacije prikupljali su podatke 2019.
godine u javnim ljekarnama diljem Hrvatske. Uključujući kriterij za odabir pacijenata bio je prisutnost
analgetika u terapiji kao i dijagnoza iz kardiovaskularnog, gastrointestinalnog ili endokrinog područja.
Podatci korišteni za analizu uključivali su opće karakteristike, povijest bolesti, medikacijsku povijest,
životne navike, prisutne alergije te terapijske probleme koje su utvrdili studenti. Alat za definiranje
terapijskih problema preuzet je od Cipolle i sur. Određena je učestalost terapijskih problema te udio
prepoznat od strane studenata. Rezultati: U istraživanje je uključeno 80 pacijenata. Prosječna dob bila je
61,88±14,96 godina. Ukupno je utvrđeno 257 terapijskih problema, a studenti su prepoznali njih 74,8%.
Lijekovi za liječenje boli uzrokovali su 21,4% ukupnih terapijskih problema, od čega su studenti prepoznali
72,72%. Najčešći uzrok problema povezan lijekovima za liječenje boli bila je nesigurnost primjene zbog
rizičnih čimbenika pacijenta, dok su najveći broj problema izazvali NASID i tramadol. Zaključak:
Lijekovi mogu biti izvor brojnih i ozbiljnih terapijskih problema ukoliko se ne koriste racionalno. Potrebno
je obratiti pažnju na lijekove za liječenje boli, od kojih su neki u bezreceptnom režimu, a pokazali su
značajan potencijal uzrokovanja terapijskih problema.

Abstract (english)

The secondary objective was to explore pharmacy students' recognition of the drug therapy problems. Subjects
and methods: The data used in this study was collected by pharmacy students in 2019 in Croatian community
pharmacies. Inclusion criteria for selecting patients were the presence of analgesic in the therapy and the
diagnosis from the cardiovascular, gastrointestinal or endocrine area. The data used for the analysis included
general characteristics of patients (age, sex, body weight and height), medication history, history of illness, social
history, allergies and drug related problems identified by students. A tool for defining therapeutic problems was
developed by Cipolle et al. The frequency of individual therapeutic problems and the proportion recognized by
students were determined. Results: 80 patients were included in the study.The mean age was 61.88±14.96 years.
A total of 257 therapeutic problems were identified, and students recognized 74.8% of them. Analgesics caused
21.4% of total therapeutic problems, of which 72.72% were recognized by students. The most common cause of
analgesic-related problems was unsafe drug due to patient risk factors, while most problems were caused by
NSAID and tramadol. Conclusion: Medications can be a source of numerous and serious therapeutic problems if
not used rationally. Importance should be given to analgesics, some of which are in non-prescription regime, and
have shown great potential for causing drug related problems.

• Keywords: terapijski problemi; analgetici; bol; racionalna farmakoterapija
• Keywords (english): drug-related problems; analgesics; pain; rational pharmacotherapy
• Language: croatian
• URN:NBN: urn:nbn:hr:163:777502
• Study programme: Title: Pharmacy; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2022-02-08 13:47:04