Implementacija usluge upravljanja farmakoteraijom s ciljem postizanja očekivanih kliničkih ishoda bolesnika s kroničnim bolestima

master's thesis

• Title (english): Implementation of Comprehensive medication management with the aim of achieving the expected treatment outcomes of patients with chronic diseases
• Author: Andrea Matijević
• Mentor: Iva Mucalo (mentor)
• Committee member: Iva Mucalo (predsjednik povjerenstva)
• Committee member: Dubravka Vitali Čepo (član povjerenstva)
• Committee member: Živka Juričić (član povjerenstva)
• Granter: University of Zagreb; Faculty of Pharmacy and Biochemistry; (Centre for applied pharmacy); Zagreb
• Defense date and country: 2021-09-10, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Pharmacy; Pharmacy

Abstract

Prevalencija kroničnih bolesti je u stalnom porastu i predstavlja veliki javnozdravstveni problem, naročito u razvijenim zemljama. Povećana prevalencija i popratni komorbiditeti često dovode do iracionalnog propisivanja lijekova čime se povećava rizik od nastanka terapijskih problema koji dodatno opterećuju pacijenta i zdravstveni sustav. Jedan od potencijalnih načina racionalizacije potrošnje lijekova je implementacija sveobuhvatne usluge upravljanja farmakoterapijom u zdravstveni sustav. Riječ je o standardiziranoj usluzi koju pružaju posebno educirani farmaceuti u svrhu identifikacije i rješavanja terapijskih problema, povećanja suradnje unutar zdravstvenog tima koji skrbi o pacijentu, poboljšanja ishoda liječenja te prevencije nastanka novih zdravstvenih problema. Obzirom da se ova usluga više godina provodi u državama diljem svijeta, cilj ovog rada bio je, na temelju publiciranih radova, istražiti utjecaj provođenja sveobuhvatne usluge upravljanja farmakoterapijom na kliničke ishode pacijenata s kroničnim bolestima. U izradi rada su korišteni znanstveni radovi iz časopisa dostupnih u bazama podataka PubMed, Medline, Web of Science te udžbenici i ostala dostupna literatura. Rezultati su pokazali da usluga upravljanja farmakoterapijom ima pozitivan utjecaj na smanjenje krvnog tlaka kod oboljelih od hipertenzije i šećerne bolesti. Također je pokazan utjecaj na smanjenje glikiranog hemoglobina HbA1c što govori o pozitivnom utjecaju upravljanja farmakoterapijom na kontrolu šećerne bolesti. Iako u manjem broju, publicirani su i radovi koji govore o pozitivnom utjecaju sveobuhvatne usluge upravljanja farmakoterapijom na poboljšanje kliničkog statusa kod osoba oboljelih od kronične opstruktivne plućne bolesti i karcinoma dojke. Integracijom usluge u zdravstveni sustav smanjuje se broj neželjenih terapijskih problema, dolazi do bolje kontrole bolesti što usporava progresiju bolesti. Također se povećava interdisciplinarna suradnja kojom se upotpunjuje zdravstvena skrb, racionalizira se potrošnja lijekova što rasterećuje zdravstveni sustav.

Abstract (english)

The prevalence of chronic diseases is constantly increasing, and it represents a major public health problem. The increased prevalence of chronic diseases and associated comorbidities lead to irrational prescribing of medicines. That increases the risk of developing drug therapy problems which additionally burdens the patient and the healthcare system. One of the potential ways to rationalize drug consumption is to implement a comprehensive medication management service in the health care system. It is a standardized service provided by trained pharmacists to identify and solve drug therapy problems, increase cooperation within the health care team, improve treatment outcomes and prevent the emergence of new health problems. Given that this service has been already implemented for many years in some countries, the aim of this paper was to show the impact of providing comprehensive medication management services on clinical outcomes of patients with chronic diseases. The research for this work has been done through academic scientific papers published in professional journals through the following databases: PubMed Central, Medline, Web of Science, as well as textbooks and other available literature. The results showed that implementing this service has a positive impact on lowering blood pressure in patients with hypertension and diabetes. The effect on the reduction of glycated hemoglobin has also been shown, which indicates a positive outcome on better control of diabetes. Also, some published studies show positive impact on the improvement of clinical status in patients with chronic obstructive pulmonary disease as well as breast cancer. Integrating this service reduces the number of unwanted drug therapy problems and improves disease control. Also, it increases multidisciplinary cooperation which complements health care, rationalizes the consumption of drugs which benefits the patients as well as the health care system.

• Keywords: ljekarnička skrb; kronične bolesti; farmakoterapija; klinički ishodi
• Keywords (english): pharmacist's care; chronic diseases; pharmacotherapy; clinical outcomes
• Language: croatian
• URN:NBN: urn:nbn:hr:163:141963
• Study programme: Title: Pharmacy; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2022-02-10 15:58:34