Određivanje minerala u dodacima prehrani za liječenje upalnih bolesti crijeva atomskom apsorpcijskom spektrometrijom

master's thesis

• Title (english): Determination of minerals in dietary supplement therapies for inflammatory bowel disease by atomic absorption spectrometry
• Author: Pavle Manzin
• Mentor: Daniela Amidžić Klarić (mentor)
• Committee member: Ana Mornar Turk (predsjednik povjerenstva)
• Committee member: Toma Keser (član povjerenstva)
• Committee member: Mario-Livio Jeličić (član povjerenstva)
• Granter: University of Zagreb; Faculty of Pharmacy and Biochemistry; (Department of pharmaceutical analysis); Zagreb
• Defense date and country: 2022-07-15, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Pharmacy; Pharmacy

Abstract

Biljke i dodaci prehrani su važan izvor biološki aktivnih sastavnica koje pozitivno utječu na zdravlje ljudi. Osim toga, primjena dodataka prehrani u stalnom je porastu. Budući da se indijski tamjanovac, justicija i kurkuma koriste u ublažavanju simptoma upalnih bolesti crijeva, cilj ovog rada bio je procijeniti kvalitetu dodataka prehrani obzirom na sadržaj kalcija i magnezija. Sadržaj navedenih minerala u analiziranim dodacima prehrani određen je plamenom tehnikom atomske apsorpcijske spektrometrije nakon postupka mikrovalne digestije. Nadalje, u analiziranim uzorcima ispitan je gubitak sušenjem prema propisu Američke Farmakopeje. Rezultati istraživanja upućuju na visoki sadržaj ovih minerala te se analizirani dodaci prehrani mogu smatrati dobrim izvorom minerala. Osim toga, svi analizirani dodaci prehrani osim jednog uzorka koji sadrži suhi ekstrakt papra zadovoljavaju USP zahtjeve obzirom na gubitak sušenjem.

Abstract (english)

Plants and dietary supplements are an important source of biologically active components that have a positive effect on human health. In addition, the use of dietary supplements is constantly increasing. Since Indian frankincense, Green chiretta and Turmeric are used to relieve the symptoms of inflammatory bowel diseases, the aim of this work was to evaluate calcium and magnesium content in dietary supplements. The content of the mentioned minerals in the analyzed food supplements was determined by the flame technique of atomic absorption spectrometry after the microwave digestion procedure. Furthermore, the analyzed samples were tested for drying loss according to the regulation of the U.S. Pharmacopoeia. The obtained results indicate a high content of these minerals, and the studied dietary supplements can be considered a good source of minerals. In addition, all analyzed dietary supplements except for one sample containing dry extract of pepper meet the USP criteria regarding drying loss.

• Keywords: kalcij; magnezij; dodaci prehrani; upalne bolesti crijeva; kurkuma; justicija; indijski tamjanovac
• Keywords (english): calcium; magnesium; dietary supplements; inflammatory bowel diseases; Turmeric; Green chiretta; Indian frankincense
• Language: croatian
• URN:NBN: urn:nbn:hr:163:312795
• Study programme: Title: Pharmacy; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Embargoed access; Embargo expiration date: 2024-07-15
• Created on: 2022-08-26 11:41:46