Neesencijalni nutrijenti u multivitaminsko-mineralnim dodacima prehrani na hrvatskom tržištu - sustavni pregled učinkovitosti, doziranosti i interakcija temeljen na dokazima

master's thesis

• Title (english): Non-essential nutrients in multivitamin-mineral food supplements on the Croatian market - an evidence-based systematic review of efficacy, dosage and interaction
• Author: Ivana Vranešić
• Mentor: Kristina Radić (mentor)
• Committee member: Kristina Radić (predsjednik povjerenstva)
• Committee member: Dubravka Vitali Čepo (član povjerenstva)
• Committee member: Andrea Brajković (član povjerenstva)
• Granter: University of Zagreb; Faculty of Pharmacy and Biochemistry; (Department of food chemistry); Zagreb
• Defense date and country: 2023-08-29, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Pharmacy; Pharmacy

Abstract

Multivitaminsko-mineralni (MVM) dodaci prehrani često su korišteni dodaci prehrani, te
kontinuirano izlaze nove varijante na tržištu. Proizvođači se često trude istaknuti svoj proizvod među
mnogima tako da uz osnovne vitamine i minerale dodaju i neesencijalne sastojke za koje postoje
dokazi da pridonose očuvanju zdravlja. No, zbog kompleksnosti formulacija MVM dodataka
prehrani, posebno zbog velikog broja sastavnica različitih fizikalno-kemijskih svojstava,
inkorporiranje dodatnih komponenti u dozama koje ostvaruju učinak predstavlja izazov koji često
ima i visoke troškove. S obzirom na velik broj različitih MVM dodataka prehrani na tržištu, svaki s
drugačijim sastavom i koncentracijama, uzimajući u obzir moguće interakcije neesencijalnih
komponenti s ostalim sastojcima i lijekovima koje osoba koristi, pružanje savjeta u ljekarničkoj
praksi postaje posebno kompleksno. Stoga se ovaj rad usmjerava na analizu najčešće prisutnih
neesencijalnih komponenti u MVM dodacima prehrani trenutno dostupnih na hrvatskom tržištu. Cilj
je pružiti znanstveno utemeljene dokaze o njihovoj učinkovitosti, dozama potrebnim za postizanje
željenih efekata te mogućim interakcijama s drugim dodacima prehrani i lijekovima. U tu svrhu, rad
je fokusiran na proučavanje beta glukana, beta karotena, inulina, inozitola, kolina, lecitina, likopena,
luteina i koenzima Q.

Abstract (english)

Multivitamin-mineral (MVM) food supplements are widely used food supplements, and new
variants are continuously appearing on the market. Manufacturers often try to differentiate their
product by adding non-essential ingredients in addition to basic vitamins and minerals, which are
proven to contribute to health. However, due to the complexity of the formulations of MVM food
supplements, especially due to the large number of components with different physico-chemical
properties, incorporating additional components in effective doses is a challenge that often has high
costs. Given the large number of different MVM food supplements on the market, each with a
different composition and concentrations, considering possible interactions of non-essential
components with other ingredients and drugs that a person uses, providing advice in pharmacy
practice becomes particularly complex. Therefore, this thesis focuses on the analysis of the most
frequently non-essential components in MVM nutritional supplements currently present on the
Croatian market. The goal is to provide scientifically based evidence on their effectiveness, the doses
needed to achieve the desired effects, and possible interactions with other nutritional supplements
and medications. For this purpose, the thesis is focused on the study of beta glucan, beta carotene,
inulin, inositol, choline, lecithin, lycopene, lutein, and coenzyme Q.

• Keywords: MVM dodaci prehrani; beta glukan; beta karoten; inulin; inozitol; kolin; lecitin; likopen; lutein; koenzim Q10
• Keywords (english): MVM supplements; beta glucans; beta carotene; inulin; inositol; choline; lecithin; lycopene; lutein; coenzyme Q10
• Language: croatian
• URN:NBN: urn:nbn:hr:163:737868
• Study programme: Title: Pharmacy - integrated undergraduate and graduate - university study; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: sveučilišni magistar farmacije (sveučilišni magistar farmacije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-04-02 12:13:15