Sigurnost primjene multivitaminsko-mineralnih dodataka prehrani

master's thesis

• Title (english): The safety of the use of multivitamin-mineral dietary supplements
• Author: Sara Paljar
• Mentor: Kristina Radić (mentor)
• Committee member: Kristina Radić (predsjednik povjerenstva)
• Committee member: Dubravka Vitali Čepo (član povjerenstva)
• Committee member: Andrea Brajković (član povjerenstva)
• Granter: University of Zagreb; Faculty of Pharmacy and Biochemistry; (Department of food chemistry); Zagreb
• Defense date and country: 2024-09-26, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Pharmacy; Pharmacy

Abstract

Multivitaminsko-mineralni (MVM) dodaci prehrani popularni su i široko korišteni dodaci
prehrani u općoj populaciji. Sadrže vitamine i minerale različitih sastava, količina sastavnica
i karakteristika te se koriste kao pomoć u dodatnom unosu esencijalnih mikronutrijenata u
organizam te za podržavanje specifičnih funkcija u organizmu kod određenih stanja
pacijenata ili u posebnim skupinama pacijenata. Iako su vrlo popularni, primjena MVM
dodataka prehrani nije u potpunosti bez rizika za zdravlje pacijenata. Poznato je da vitamini
i minerali, kao sastavnice MVM dodataka prehrani, mogu ulaziti u različite interakcije s
lijekovima i zdravstvenim stanjima pacijenata. Također, važno je imati na umu raspon doza
optimalnog unosa vitamina i minerala te sigurnost primjene istih u posebnim skupinama
pacijenata što uključuje djecu, trudnice i dojilje. Sve navedeno može uzrokovati smanjenje
ili povećanje učinaka lijekova ili sastavnica MVM dodataka prehrani ili može povećati rizik
od nastanka štetnih ishoda kod pacijenata. U ovom diplomskom radu pružen je sustavni
pregled i detaljna objašnjenja najvažnijih interakcija vitamina i minerala, kao sastavnica
MVM dodataka prehrani, s lijekovima i zdravstvenim stanjima pacijenata te sigurnost
primjene istih kod djece, trudnica i dojilja. Rad također naglašava ključnu ulogu ljekarnika u
savjetovanju pacijenata o primjeni MVM dodataka prehrani.

Abstract (english)

Multivitamin/mineral (MVM) dietary supplements are popular and widely used dietary
supplements in the general population. They contain vitamins and minerals of different
compositions, amounts of components, and characteristics. They are used to help with
additional intake of essential micronutrients in the body and to support specific functions in
the body in certain patients' conditions or special groups of patients. Although they are very
popular, the use of MVM dietary supplements is not entirely without risk to patient's health.
It is known that vitamins and minerals, as components of MVM dietary supplements, can
interact with drugs and different patients' health conditions. Also, it is important to take into
account the range of doses for optimal intake of vitamins and minerals and the safety of their
use in special groups of patients including children, pregnant women, and breastfeeding
women. All of the above can cause a decrease or increase in the drug effect or MVM dietary
supplement components or may increase the risk of patient's adverse outcomes. This diploma
thesis provides a systematic overview and detailed explanations of the most important
interactions of vitamins and minerals, as components of MVM dietary supplements, with
drugs and patients' health conditions, as well as the safety of their use in children, pregnant
women, and breastfeeding women. The thesis also emphasizes the key role of the pharmacist
in the counseling of patients on the use of MVM dietary supplements.

• Keywords: dodaci prehrani; multivitaminsko-mineralni dodaci prehrani; vitamini; minerali; prehrambeni referentni unos; nutrivigilancija
• Keywords (english): dietary supplements; multivitamin mineral supplements; vitamins; minerals; dietary reference intake; nutrivigilance
• Language: croatian
• URN:NBN: urn:nbn:hr:163:036225
• Study programme: Title: Pharmacy - integrated undergraduate and graduate - university study; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: sveučilišni magistar farmacije (sveučilišni magistar farmacije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-10-17 13:30:48