| Abstract | Šećerna bolest tipa 2 najčešći je oblik šećerne bolesti i jedan od najvećih problema današnjega javnoga zdravstva zbog
visoke prevalencije i velikih troškova liječenja. Karakterizirana je inzulinskom rezistencijom, a tijekom vremena
dolazi i do relativnog nedostatka inzulina što rezultira hiperglikemijom. Cilj studije bio je ispitati uspješnost bolesnika
sa šećernom bolesti tipa 2 šest mjeseci nakon boravka u dnevnoj bolnici Zavoda za endokrinologiju, dijabetes i bolesti
metabolizma Kliničke bolnice Dubrava u Zagrebu. Uspješnim bolesnikom smatrani su svi bolesnici koji su postigli
HbA1c <7% i GUP <7 mmol/L. Opservacijska, prospektivna studija pratila je 69 bolesnika koji su udovoljili
kriterijima uključivanja- neregulirana šećerna bolest i pojavljivanje na zakazanom pregledu nakon 6 mjeseci. Bolesnici
su prisustovali petodnevnom program Dijabetološke dnevne bolnice u kojoj su prolazili sveobuhvatnu edukaciji o
životu sa šećernom bolesti. Na uzorku od 69 ispitanika prosječne starosne dobi 63,3 ± 9,8 godina godina izmjerena je,
na početku studije, prosječna vrijednost GUP 11,8 ± 4,4 mmol/L i HbA1c koji je iznosio 9,4 ± 1,6 %. Sekundarni
ciljevi koji su bili praćeni su tjelesna masa, ITM, opseg struka, trigliceridi, LDL, HDL i ukupni kolesterol koji su
redom iznosili 91,1 ± 21,5 kg; 32,4 ± 7,0 kg/m2; 107,3 ± 15,0 cm; 2,2 ± 2,5 mmol/L; 3,0 ± 1,1 mmol/L; 1,2 ± 0,3
mmol/L i 5,1 ± 1,3 mmol/L. U prosjeku je otkriveno 5,6 ± 2,6 dijagnoza i korišteno 5,7 ± 2,6 lijekova. Studija je
pokazala statistički značajne rezultate u sniženju razina HbA1c (p < 0,00) i GUP (p = 0,002), kao i triglicerida (p =
0,002), dok su ostali parametri pokazali silazni trend bez statistički značajne razlike. Od sociodemografskih i kliničkih
obilježja, jedino je spol imao statistički značajan utjecaj na sniženje HbA1c. Muškarci su, naime, bili uspješniji.
Ovakav tip edukacije pokazao se uspješnim u sniženju razina GUP i HbA1c što bi dugoročno moglo smanjiti
komplikacije ove bolesti, poboljšati kvalitetu života te smanjiti troškove liječenja. |
| Abstract (english) | Type 2 diabetes is the most common form of diabetes and one of the biggest problems of today’s healthcare due to
high prevalence and high costs. It is characterized by insulin resistance, and relative deficiency of insulin occurs over
time which then results in hyperglycaemia. The aim of this study was to examine the success of patients suffering type
2 diabetes six months after spending time in the daily hospital of Endocrinology, diabetes and metabolism disease
Ward, University Hospital Dubrava. A successful patient was considered to reach HbA1c <7 % and plasma glucose <7
mmol/L. The observational, prospective study followed 69 patients who met including criterias- they had unregulated
diabetes type 2 and they showed up on a scheduled meeting six month after. In the hospital they attended a five-day
systemic education about life with diabetes type 2. The study included 69 examinees with median age 63,3 ± 9,8 years
whose plasma glucose was 11,8 ± 4,4 mmol/L and HbA1c 9,4 ± 1,6 % in average. Secondary outcomes which were
measured were body weight, BMI, waist circumference, triglycerides, LDL, HDL and total cholesterol whose levels
were by order 91,1 ± 21,5 kg; 32,4 ± 7,0 kg/m2; 107,3 ± 15,0 cm; 2,2 ± 2,5 mmol/L; 3,0 ± 1,1 mmol/L; 1,2 ± 0,3
mmol/L i 5,1 ± 1,3 mmol/L. In average, patients had 5,6 ± 2,6 diagnoses and used 5,7 ± 2,6 medicines. The study
showed statistically significant results in lowering levels of plasma glucose (p = 0,002), HbA1c (p < 0,00), and
triglycerides (p = 0,002) while the other parameters showed a descending trend, but no statistically significant results.
From the sociodemographic and clinical factors, only gender had a statistically significant influence on lowering levels
of HbA1c. Men were more successful than women. This type of education seems to have success in lowering plasma
glucose and HbA1c levels which could result in decreased incidence of complications, improved quality of life and
reduced treatment costs. |
