Usporedba dvije klasične analitičke metode za određivanje sadržaja kalcija u dodacima prehrani

master's thesis

• Title (english): Comparison of two classic analytical methods for determining calcium content in food supplements
• Author: Lucija Bušljeta
• Mentor: Jasna Jablan (mentor)
• Committee member: Jasna Jablan (predsjednik povjerenstva)
• Committee member: Suzana Inić (član povjerenstva)
• Committee member: Živka Juričić (član povjerenstva)
• Granter: University of Zagreb; Faculty of Pharmacy and Biochemistry; (Department of analytical chemistry); Zagreb
• Defense date and country: 2019-09-12, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Pharmacy; Pharmacy

Abstract

Kalcij je najzastupljeniji mineral u tijelu čovjeka. Kao takav, sudjeluje u regulaciji niza biokemijskih
procesa i njegova neravnoteža dovodi do ozbiljnih funkcionalnih poremećaja. Narušavanje homeostaze
kalcija u organizmu može nastati uslijed nedovoljnog uzimanja kalcija putem prehrane. Deficijenciju
kalcija moguće je korigirati korištenjem dodataka prehrani s kalcijem. Cilj ovog rada je usporediti dvije
klasične analitičke metode za određivanje sadržaja kalcija u odabranim dodacima prehrani. Korištene
metode su kompleksometrijska titracija i ionska izmjena, uz naknadnu titraciju. Dobiveni su rezultati
pokazali da je kompleksometrijska titracija bila uspješnija u određivanju kalcija. Naime, usporedbom
dobivenih vrijednosti sadržaja kalcija u ispitivanim uzorcima s deklariranim vrijednostima pomoću dvije
analitičke metode kompleksometrijska titracija nametnula se kao metoda izbora za određivanje kalcija u
dodacima prehrani.

Abstract (english)

Calcium is one of the most prevalent minerals in a human body. As such, it is an essential element for the
regulation of many biochemical processes, which is to say that its imbalance can lead to serious functional
disorders. Changes in the homeostasis of calcium in an organism can appear when person does not consume
sufficient amount of calcium in food. Aforementioned changes in calcium homeostasis, or a word calcium
deficiency, can be balanced again by using food supplements which contain calcium. The aim of this paper
is to compare which of two classic analytical methods is better for determining amount of calcium in food
supplements. In order to reach the goal, two methods were used: complexometric titration and ion-exchange
with titration afterward. Results had shown that complexometric titration is more successful for the
determination of calcium. Furthermore, by comparing the values of amount of calcium in both of the used
brands with declared amount of the calcium on the products complexometric titration has proved as a
method of choice for determination of calcium in food supplements.

• Keywords: kalcij; dodaci prehrani; titracija; ionska izmjena
• Keywords (english): calcium; food supplemets; titration; ion exchange
• Language: croatian
• URN:NBN: urn:nbn:hr:163:436948
• Study programme: Title: Pharmacy; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2020-03-05 13:09:30