master's thesis
Thermodynamics of cyclopalladation of 4-dimethylaminoazobenzene

Boris Prohaska (2015)
Sveučilište u Zagrebu
Farmaceutsko-biokemijski fakultet
Zavod za opću i anorgansku kemiju
Metadata
TitleTermodinamika ciklopaladiranja 4-dimetilaminoazobenzena
AuthorBoris Prohaska
Mentor(s)Ana Budimir (thesis advisor)
Abstract
U ovom radu ispitana je kinetika i mehanizam reakcije PdCl2(DMF)2 s 4-dimetilaminoazobenzenom u N,N-dimetilformamidu. Mjerenja su izvršena pod uvjetima pseudo-prvog reda tj. u velikom molarnom suvišku PdCl2(DMF)2 u odnosu na 4-dimetilaminoazobenzen te pri različitim temperaturama. Rezultati kinetičkih istraživanja pokazali su da se u ovim eksperimentalnim uvjetima reakcije monopaladiranja, odnosno dipaladiranja, odvijaju u dva uzastopna koraka. U prvom brzom koraku dolazi do nastajanja mononuklearnog, LPdCl2(DMF), odnosno monociklopaladiranog adukta L[PdCl2(DMF)]2 nakon čega slijedi spori korak u kojem dolazi do pucanja orto C-H veze i nastajanja nove Pd-C veze. Aktivacijski parametri, ΔH, ΔS te ΔEa za oba reakcijska koraka su određeni i diskutirani.
Keywordsazobenzene cyclopalladation kinetics mechanisms
Parallel title (English)Thermodynamics of cyclopalladation of 4-dimethylaminoazobenzene
Committee MembersAna Budimir
Tin Weitner
Viktor Pilepić
GranterSveučilište u Zagrebu
Farmaceutsko-biokemijski fakultet
Lower level organizational unitsZavod za opću i anorgansku kemiju
PlaceZagreb
StateCroatia
Scientific field, discipline, subdisciplineBIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Study programme typeuniversity
Study levelintegrated undergraduate and graduate
Study programmePharmacy
Academic title abbreviationmag. pharm.
Genremaster's thesis
Language Croatian
Defense date2015-09-30
Parallel abstract (English)
In this work the kinetics and mechanism of reactions of PdCl2(DMF)2 with azobenzene and 4-dimethylaminoazobenzene in N,N-dimethylformamide were examined. The measurements were conducted under pseudo first order which means that one of the reactant was in molar excess, PdCl2(DMF)2. It was found that the mono- and dicyclopalladation reactions of azobenzenes proceed in two consecutive processes, adduct formation and palladation steps. The rate-determining step in both palladations is the breaking of the ortho C-H bond. From specific rate constants can be seen that the substitution of azobenzene significantly affect on the rate of complexation. From the resaults we see that by increasing the temperature we came to increase the constance rate.
Parallel keywords (Croatian)azobenzeni ciklopaladiranje kinetika mehanizam
Resource typetext
Access conditionAccess restricted to students and staff of home institution
Terms of usehttp://rightsstatements.org/vocab/InC/1.0/
URN:NBNhttps://urn.nsk.hr/urn:nbn:hr:163:246888
CommitterPetra Gašparac