Secondary deuterium isotope effects in some S N1 and E2 reactions

Scientific paper - Original scientific paper

• Author: S. Ašperger
• Author: N. Ilakovac
• Author: D . Pavlović
• Author's institution: University of Zagreb; Faculty of Pharmacy and Biochemistry
• Scientific / art field, discipline and subdiscipline: NATURAL SCIENCES; Chemistry

Abstract (english)

An a-deuterium isotope effect kH/kn of 170/o was found in the
E 2 reaction of 2-phenylethyl-l,l-d2 bromide with sodium ethoxide
in ethanol. This supports the Streitwieser change-of-hybridization
theory and the associated explanation of the absence of such effects
in S N2 reactions as being due to the proximity of the incoming
group. The magnitude of the ~- and a-deuterium isotope effects in the
SNl and E2 reactions of some alkylsulphonium salts were determined
and compared with the isotope effects of the corresponding
alkyl-halides. An explanation for these differences is given.

• Language: english
• Publication type: Scientific paper - Original scientific paper
• Publication status: Published
• Peer review: Peer review - international
• Publication version: Published version
• Journal title: Croatica Chemica Acta
• Numbering: vol. 34, no. 1, pp. 7-12
• p-ISSN: 0011-1643
• e-ISSN: 1334-417X
• URN:NBN: urn:nbn:hr:163:358235
• Publication: 1962
• Document URL: https://hrcak.srce.hr/208414
• Type of resource: Text
• Access conditions: Open access
• Created on: 2020-05-11 14:38:18