Farmakoterapijske specifičnosti najčešćih anestetika u osoba starije životne dobi

Professional paper - Review paper

• Author: Eva Perčić
• Author: Jasminka Peršec
• Author: Ana-Marija Domijan
• Author: Petra Turčić
• Author's institution: University of Zagreb; Faculty of Pharmacy and Biochemistry; (Department of pharmaceutical botany)
• Author's institution: University of Zagreb; Faculty of Pharmacy and Biochemistry; (Department of pharmacology)
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Pharmacy; Pharmacy

Abstract (english)

Anaesthesia is a procedure which leads the patient to a state of
insensitivity. lt is divided to general and local or regional anesthesia.
General anesthetics can be divided into inhaled and intravenous, besides
them opioid analgesics and neuromuscular blockers are also used in anesthesia.
Whenever possible, regional anesthesia is preferred, especially in the elderly. The
older population is considered to be all people over the age of 65. Aging is a progressive
process characterized by changes in the structure and function of organs
and tissues. The most significant changes occur in the cardiovascular, respiratory,
nervous and hepatorenal system. Also the ability to regulate body temperature
is reduced, what is the problem during surgical procedures. Pharmacodynamic
and pharmacokinetic properties of drugs may change, resulting in greater
sensitivity of geriatric patients to anesthetics, thereby increasing the risk of
adverse effects. To achieve the same clinical effect as in younger subjects, dose
reduction of general and local anesthetics, opioid analgetics, sedatives and neuromuscular
blocking agents is required.

• Keywords (croatian): anestezija; anestetici; gerijatrijski pacijenti
• Language: croatian
• Publication type: Professional paper - Review paper
• Publication status: Published
• Peer review: Peer review - domestic
• Publication version: Published version
• Journal title: Farmaceutski glasnik
• Numbering: vol. 76, no. 1, pp. 9-33
• p-ISSN: 0014-8202
• URN:NBN: urn:nbn:hr:163:871253
• Publication: 2020
• Type of resource: Text
• Access conditions: Open access
• Created on: 2020-06-05 11:14:34