Farmakoterapijske specifičnosti najčešćih anestetika u osoba starije životne dobi

Stručni rad - Pregledni rad

• Autor: Eva Perčić
• Autor: Jasminka Peršec
• Autor: Ana-Marija Domijan
• Autor: Petra Turčić
• Autorova ustanova: Sveučilište u Zagrebu; Farmaceutsko-biokemijski fakultet; (Zavod za farmaceutsku botaniku)
• Autorova ustanova: Sveučilište u Zagrebu; Farmaceutsko-biokemijski fakultet; (Zavod za farmakologiju)
• Znanstveno / umjetničko područje, polje i grana: BIOMEDICINA I ZDRAVSTVO; Farmacija; Farmacija

Sažetak (engleski)

Anaesthesia is a procedure which leads the patient to a state of
insensitivity. lt is divided to general and local or regional anesthesia.
General anesthetics can be divided into inhaled and intravenous, besides
them opioid analgesics and neuromuscular blockers are also used in anesthesia.
Whenever possible, regional anesthesia is preferred, especially in the elderly. The
older population is considered to be all people over the age of 65. Aging is a progressive
process characterized by changes in the structure and function of organs
and tissues. The most significant changes occur in the cardiovascular, respiratory,
nervous and hepatorenal system. Also the ability to regulate body temperature
is reduced, what is the problem during surgical procedures. Pharmacodynamic
and pharmacokinetic properties of drugs may change, resulting in greater
sensitivity of geriatric patients to anesthetics, thereby increasing the risk of
adverse effects. To achieve the same clinical effect as in younger subjects, dose
reduction of general and local anesthetics, opioid analgetics, sedatives and neuromuscular
blocking agents is required.

• Ključne riječi (hrvatski): anestezija; anestetici; gerijatrijski pacijenti
• Jezik: hrvatski
• Vrsta publikacije: Stručni rad - Pregledni rad
• Status objave: Objavljen
• Vrsta recenzije: Recenziran - domaća recenzija
• Verzija publikacije: Objavljena verzija rada (izdavačev PDF)
• Naslov časopisa: Farmaceutski glasnik
• Brojčani podaci: vol. 76, br. 1, str. 9-33
• p-ISSN: 0014-8202
• URN:NBN: urn:nbn:hr:163:871253
• Datum objave publikacije: 2020
• Vrsta resursa: Tekst
• Prava pristupa: Otvoreni pristup
• Datum i vrijeme pohrane: 2020-06-05 11:14:34