Terapijski problemi u liječenju pacijenata sa shizofrenijom i depresijom

professional thesis

• Author: Margareta Bego
• Mentor: Miroslav Herceg (mentor); MBZ: 284711
• Committee member: Lidija Bach-Rojecky
• Committee member: Miroslav Herceg; MBZ: 284711
• Committee member: Vesna Bačić Vrca
• Granter: University of Zagreb; Faculty of Pharmacy and Biochemistry; Zagreb
• Defense date and country: 2016, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Pharmacy; Pharmacy

Abstract

Cilj istraživanja: Cilj ovog rada je pregledno prikazati glavne terapijske probleme u liječenju pacijenata sa shizofrenijom i depresijom i osvrnuti se na važnost uloge koju ljekarnici mogu imati u njihovom zbrinjavanju.
Ispitanici i metode: U tu svrhu pretraženi su relevantni psihijatrijski dijagnostički priručnici i trenutno važeće terapijske smjernice, znanstvena i stručna literatura, publikacije stručnih udruga i institucija, baza lijekova Agencije za lijekove i medicinske proizvode te drugi raspoloživi izvori.
Rezultati: Identificirana su tri glavna terapijska problema u liječenju pacijenata sa shizofrenijom i depresijom koja mogu negativno utjecati na željeni ishod liječenja: nuspojave psihofarmaka, slaba adherencija pacijenata na terapiju te primjena velikog broja lijekova koja stvara potencijal za nastanak interakcija lijekova i medikacijskih pogrešaka.
Zaključak: Terapijske probleme potrebno je prepoznati i pravovremeno zbrinuti ili prevenirati kako bi pacijent mogao postići terapijski cilj. Ljekarnici se, kao karika između liječnika i bolesnika, nalaze u idealnom položaju za intervenciju u prepoznatim terapijskim problemima s potencijalom za doprinos u boljem ishodu liječenja za bolesnika. Stoga, postoji potreba za većim uključenjem ljekarnika u skrb za mentalno zdravlje kao i za praćenjem učinaka tog uključenja.

Abstract (english)

Aim: The aim of this paper is to do a review of main drug-related problems in the treatment of patients with schizophrenia and depression and to make a reference to the importance of the role that pharmacists could have in their managment.
Subjects and method: For this purpose relevant psychiatric diagnostic manuals, currently relevant treatment guidelines, scientific articles and expert perspectives, publications of professional associations and institutions, Agency for Medicinal Products and Medical Devices' database and other available resources were searched.
Results: Three main drug-related problems in the treatment of patients with schizophrenia and depression were identified, that may have a negative impact on preferred treatment outcome: adverse drug reactions of psychotropic medications, poor medication adherence and use of multiple medication which creates a potential for drug-drug interactions and medication errors.
Conclusion: Drug-related problems should be identified and managed or prevented in timely manner in order to achieve the therapeutic goal. Pharmacists, as the link between a physician and a patient, are found to be in an ideal position for intervention in identified drug-related problems with potential of contribution in better treatment outcome. Therefore, there is a need for greater involvement of pharmacists in mental health care and also a need for monitoring of its effects.

• Keywords: shizofrenija; depresija; antidepresivi; antipsihotici; psihofarmaci; nuspojave lijekova; interakcije lijekova; medikacijske pogreške
• Keywords (english): schizophrenia; depression; antidepressants; antipsychotics; psychotropic medications; side effects of drugs; drug-drug interactions; medication errors
• Language: croatian
• URN:NBN: urn:nbn:hr:163:670895
• Study programme: Title: Clinical pharmacy; Study programme type: university; Study level: postgraduate specialist; Academic / professional title: sveučilišni/a magistar/sveučilišna magistra kliničke farmacije (sveučilišni/a magistar/sveučilišna magistra kliničke farmacije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2016-03-31 10:33:03