Znanstveni rad - Izvorni znanstveni rad
Urates in exhaled breath condensate of children with obstructive sleep apnea

Vlasic, Vukmir; Trifunovic, Jasenka; Cepelak, Ivana; Nimac, Petra; Zrinski Topic, Renata; Dodig, Slavica (2011)
Podaci o radu
Jezik rada engleski
Naslov (engleski)Urates in exhaled breath condensate of children with obstructive sleep apnea
AutorVlasic, Vukmir
Trifunovic, Jasenka
Cepelak, Ivana
Nimac, Petra
Zrinski Topic, Renata
Dodig, Slavica
Sažetak rada (engleski)
Background: Urate levels may be a marker of oxidative stress. The aim of the present study was to find out are there any differences in urate concentrations in exhaled breath condensate (EBC) between children with obstructive sleep apnea (OSA) and healthy children. Materials and methods: EBC was collected in children with obstructive sleep apnea (OSA) and clinically healthy children. Urate measurements in EBC and serum were performed by enzymatic co-lor test. Results: The higher concentration of urates in EBC of children with OSA than clinically healthy chil-dren indicate the oxidative stress in their airways. Since there was no significant difference in serum concentration of urates between children with OSA and healthy children, it could be considered that urates are sintetized in the airways of children with OSA. Conclusions: The present study indicated that urates in EBC (but not in serum) may be used as a marker of local synthesis of antioxidant compounds, but definitive conclusion must be supported by investigations involving larger number of participants.
Ključne riječi (engleski)exhaled breath condensate obstructive sleep apnea oxidative stress urates
Vrsta radaznanstveni rad - izvorni znanstveni rad
Status objave radaobjavljen
Vrsta recenzijerecenziran
Naslov časopisaBiochemia medica : Biochemia medica
Brojčani podaci2011, Vol. 21, br. 2, str. 139-144
ISSN1330-0962
Datumdatum objave publikacije: 15.06.2011.
URL radahttp://hrcak.srce.hr/69657
Znanstveno područjeBIOMEDICINA I ZDRAVSTVO
Farmacija
Medicinska biokemija
UstanovaSveučilište u Zagrebu, Farmaceutsko-biokemijski fakultet
URN:NBNhttps://urn.nsk.hr/urn:nbn:hr:163:543156