prikaz prve stranice dokumenta Reactions with N-(1-benzotriazolylcarbonyl)-amino acids. IV. The use of N-(1-benzotriazolylcarbonyl)-amino acid derivates in peptide synthesis
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Reactions with N-(1-benzotriazolylcarbonyl)-amino acids. IV. The use of N-(1-benzotriazolylcarbonyl)-amino acid derivates in peptide synthesis
Croatica Chemica Acta, 63 (1991), 4; 565-578. urn:nbn:hr:163:408285
Zorc, Branka; Karlović, G.; Butula, Ivan

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Zorc, B., Karlović, G. i Butula, I. (1991). Reactions with N-(1-benzotriazolylcarbonyl)-amino acids. IV. The use of N-(1-benzotriazolylcarbonyl)-amino acid derivates in peptide synthesis. Croatica Chemica Acta, 63. (4), 565-578. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:163:408285

Zorc, Branka, et al. "Reactions with N-(1-benzotriazolylcarbonyl)-amino acids. IV. The use of N-(1-benzotriazolylcarbonyl)-amino acid derivates in peptide synthesis." Croatica Chemica Acta, vol. 63, br. 4, 1991, str. 565-578. https://urn.nsk.hr/urn:nbn:hr:163:408285

Zorc, Branka, G. Karlović i Ivan Butula. "Reactions with N-(1-benzotriazolylcarbonyl)-amino acids. IV. The use of N-(1-benzotriazolylcarbonyl)-amino acid derivates in peptide synthesis." Croatica Chemica Acta 63, br. 4 (1991): 565-578. https://urn.nsk.hr/urn:nbn:hr:163:408285

Zorc, B., Karlović, G. i Butula, I. (1991) 'Reactions with N-(1-benzotriazolylcarbonyl)-amino acids. IV. The use of N-(1-benzotriazolylcarbonyl)-amino acid derivates in peptide synthesis', Croatica Chemica Acta, 63(4), str. 565-578. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:163:408285 (Datum pristupa: 03.12.2024.)

Zorc B, Karlović G, Butula I. Reactions with N-(1-benzotriazolylcarbonyl)-amino acids. IV. The use of N-(1-benzotriazolylcarbonyl)-amino acid derivates in peptide synthesis. Croatica Chemica Acta [Internet]. 26.03.1991. [pristupljeno 03.12.2024.];63(4):565-578. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:163:408285

B. Zorc, G. Karlović i I. Butula, "Reactions with N-(1-benzotriazolylcarbonyl)-amino acids. IV. The use of N-(1-benzotriazolylcarbonyl)-amino acid derivates in peptide synthesis", Croatica Chemica Acta, vol. 63, br. 4, str. 565-578, Ožujak 1991. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:163:408285. [Citirano: 03.12.2024.]

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Naslov (engleski)Reactions with N-(1-benzotriazolylcarbonyl)-amino acids. IV. The use of N-(1-benzotriazolylcarbonyl)-amino acid derivates in peptide synthesis
AutorBranka Zorc
AutorG. Karlović
AutorIvan Butula
MBZ: 6372
Autorova ustanovaSveučilište u Zagrebu
Farmaceutsko-biokemijski fakultet
(Zavod za farmaceutsku kemiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Farmacija
Farmacija
Sažetak (engleski)
The use of the 1-benzotriazolylearbonyl-(Bte)-group as an N-protecting and N-activating group in the synthesis of peptides was investigated. Removal of the Btc group from N-Btc-amino acids, their esters and amides under acidic conditions is possible, but has no advantages over removal of benzyloxyearbonyl-(Z)-group. N-Btc-amino acid esters react with Z-amino acids or Z-dipeptides yielding Z-dipeptide and Z-tripeptide esters, respcetively. This process is aceompanied with separation of benzotriazole and C02. Advantages and disadvantages of this method of peptide bond formation are discussed.
Ključne riječi (hrvatski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCroatica Chemica Acta
Brojčani podacivol. 63, br. 4, str. 565-578
p-ISSN0011-1643
e-ISSN1334-417X
URN:NBNurn:nbn:hr:163:408285
Datum objave publikacije1991-03-26
URL dokumentahttps://hrcak.srce.hr/176511
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2018-02-22 14:17:27