prikaz prve stranice dokumenta TNF-alpha, CXCL8, big ET-1 and hsCRP in patients with chronic obstructive pulmonary disease
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TNF-alpha, CXCL8, big ET-1 and hsCRP in patients with chronic obstructive pulmonary disease
Croatica Chemica Acta, 81 (2008), 1; 211-217. urn:nbn:hr:163:459731
Marević, Sanja; Petrik, József; Vrkić, Nada; Popović-Grle, Sanja; Žanić-Grubišić, Tihana; Čepelak, Ivana

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Marević, S., Petrik, J., Vrkić, N., Popović Grle, S., Žanić Grubišić, T. i Čepelak, I. (2008). TNF-alpha, CXCL8, big ET-1 and hsCRP in patients with chronic obstructive pulmonary disease. Croatica Chemica Acta, 81. (1), 211-217. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:163:459731

Marević, Sanja, et al. "TNF-alpha, CXCL8, big ET-1 and hsCRP in patients with chronic obstructive pulmonary disease." Croatica Chemica Acta, vol. 81, br. 1, 2008, str. 211-217. https://urn.nsk.hr/urn:nbn:hr:163:459731

Marević, Sanja, József Petrik, Nada Vrkić, Sanja Popović Grle, Tihana Žanić Grubišić i Ivana Čepelak. "TNF-alpha, CXCL8, big ET-1 and hsCRP in patients with chronic obstructive pulmonary disease." Croatica Chemica Acta 81, br. 1 (2008): 211-217. https://urn.nsk.hr/urn:nbn:hr:163:459731

Marević, S., et al. (2008) 'TNF-alpha, CXCL8, big ET-1 and hsCRP in patients with chronic obstructive pulmonary disease', Croatica Chemica Acta, 81(1), str. 211-217. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:163:459731 (Datum pristupa: 09.12.2024.)

Marević S, Petrik J, Vrkić N, Popović Grle S, Žanić Grubišić T, Čepelak I. TNF-alpha, CXCL8, big ET-1 and hsCRP in patients with chronic obstructive pulmonary disease. Croatica Chemica Acta [Internet]. 2008. [pristupljeno 09.12.2024.];81(1):211-217. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:163:459731

S. Marević, J. Petrik, N. Vrkić, S. Popović Grle, T. Žanić Grubišić i I. Čepelak, "TNF-alpha, CXCL8, big ET-1 and hsCRP in patients with chronic obstructive pulmonary disease", Croatica Chemica Acta, vol. 81, br. 1, str. 211-217, 2008. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:163:459731. [Citirano: 09.12.2024.]

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Naslov (engleski)TNF-alpha, CXCL8, big ET-1 and hsCRP in patients with chronic obstructive pulmonary disease
AutorSanja Marević https://orcid.org/0000-0003-4465-1457
AutorJózsef Petrik
AutorNada Vrkić
AutorSanja Popović-Grle
AutorTihana Žanić-Grubišić
AutorIvana Čepelak
Autorova ustanovaSveučilište u Zagrebu
Farmaceutsko-biokemijski fakultet
(Zavod za medicinsku biokemiju i hematologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Farmacija
Medicinska biokemija
Sažetak (engleski)
COPD (chronic obstructive pulmonary disease) is a chronic progressive inflammatory disease characterised by limitations in lung airflow that is not fully reversible. The concentrations and correlations of TNF-á, CXCL8, big ET-1 and hsCRP were investigated in healthy non-smokers, healthy smokers and patients with COPD in order to study their possible role in the pathophysiology of COPD. The concentrations of TNF-á, CXCL8 and big ET-1 were not statistically different between the experimental groups. No significant differences for the measured analytes were found between smokers and the non-smokers in the control group. The Spearman coefficient of correlation between the concentrations of TNF-á and CXCL8 was r = 0.638 (p<0.0001). However, the concentration of hsCRP was significantly higher in patients with COPD than in the control group (p = 0.0004). hsCRP proved to be a more sensitive diagnostic parameter than TNF-á, CXCL8 and big ET-1 in the systemic circulation in patients with COPD.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCroatica Chemica Acta
Brojčani podacivol. 81, br. 1, str. 211-217
p-ISSN0011-1643
e-ISSN1334-417X
URN:NBNurn:nbn:hr:163:459731
Datum objave publikacije2008
URL dokumentahttps://hrcak.srce.hr/23450
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2020-04-21 14:55:47