Čimbenici koji mogu utjecati na učinkovitu i sigurnu primjenu nesteroidnih antiinfamatornih lijekova

Stručni rad - Stručni rad

• Autor: Dalia Vađunec
• Autor: Lidija Bach-Rojecky
• Autorova ustanova: Sveučilište u Zagrebu; Farmaceutsko-biokemijski fakultet; (Zavod za farmakologiju)
• Znanstveno / umjetničko područje, polje i grana: BIOMEDICINA I ZDRAVSTVO; Farmacija; Farmacija

Sažetak (engleski)

The community pharmacist challenges with the dispensing of
medicines for the pain treatment, whether they are prescribed
or recommended as over-the-counter medicines in self-treatment. It is very
important to know pharmacodynamic and pharmacokinetic characteristics of
individual drugs, but also to understand other factors that may influence their
efficacy and safety. The fact that everyone differs due to the influence of genes,
but also in impact of environmental factors on (de)activation genes, results in
different responses to drugs. Implementations of personalized therapy concept
in pharmaceutical care is a huge challenge for pharmacists as well as for the
other health-care providers. Pharmacists, with their specific knowledge and
skills related to drugs are in position to tailor personalized therapy approach.
This paper presents the pharmacological characteristics of nonsteroidal
anti-inflammatory drugs with emphasis on the impact of specific genetic variations
on their efficacy and safety.

• Ključne riječi (hrvatski): nesteroidni antiinflamatorni lijekovi; NSAIL; personalizirani pristup; farmakogenetika, farmakogenomika
• Jezik: hrvatski
• Vrsta publikacije: Stručni rad - Stručni rad
• Status objave: Objavljen
• Vrsta recenzije: Recenziran - domaća recenzija
• Verzija publikacije: Objavljena verzija rada (izdavačev PDF)
• Naslov časopisa: Farmaceutski glasnik
• Brojčani podaci: vol. 77, br. 9-10, str. 479-490
• p-ISSN: 0014-8202
• URN:NBN: urn:nbn:hr:163:750680
• Datum objave publikacije: 2021
• Vrsta resursa: Tekst
• Prava pristupa: Otvoreni pristup
• Datum i vrijeme pohrane: 2021-12-15 15:43:30