| Sažetak | Korijandar (Coriandrum sativum L.) je aromatična zeljasta biljka koja pripada porodici štitarki
(Apiaceae). Plodovi se koriste kao začin, a poznato je da posjeduju i ljekovita svojstva kao što su
antibakterijska, antifungalna, antidijabetička, hipolipemijska i hepatoprotektivna. U okviru ovog
diplomskog rada provedena je kvalitativna i kvantitativna fitokemijska analiza eteričnog ulja u osam
komercijalno dostupnih uzoraka korijandrovog ploda s hrvatskog tržišta. Farmakopejskom metodom
destilacije pomoću vodene pare utvrđeno je da analizirani uzorci plodova in toto sadrže 4,14 mL/kg
- 17,17 mL/kg eteričnog ulja, a uzorci plodova u in pulvere 9,12 mL/kg – 14,13 mL/kg eteričnog ulja.
Svi analizirani uzorci farmaceutske su kakvoće s obzirom na farmakopejski zahtjev za sadržajem
najmanje 3 mL/kg eteričnog ulja. Analiza izoliranog eteričnog ulja provedena metodom plinske
kromatografije spregnute s tandemskom spektrometrijom masa (GC-MS/MS) pokazala je da je
glavna sastavnica korijandrovog eteričnog ulja linalol (61,83 % - 87,73 %). Ostale značajnije
zastupljene sastavnice su γ-terpinen (3,29 % - 9,32 %), α-pinen (0,74 % - 7,15 %), kamfor (4,08 % -
6,12 %), geranil acetat (2,96 % - 6,29 %), p-cimen (0,74 % - 3,01 %), limonen (0,60 % - 4,10 %),
geraniol (0,15 % - 3,50 %) i α-terpineol (0,30 % - 0,50 %). Rad ukazuje na važnost osiguravanja
kakvoće biljnih droga koji se koriste u fitoterapiji i aromaterapiji, u cilju postizanja učinkovite i
sigurne primjene. |
| Sažetak (engleski) | Coriander (Coriandrum sativum L.) is an aromatic herbaceous plant belonging to the Apiaceae
family. The fruits are used as a spice and are known to possess medicinal properties such as
antibacterial, antifungal, antidiabetic, hypolipidemic, and hepatoprotective effects. This diploma
thesis conducted a qualitative and quantitative phytochemical analysis of the essential oil in eight
commercially available samples of coriander seeds from the Croatian market. Using the
pharmacopoeial method of steam distillation, it was determined that the analyzed samples of fruits
in toto contain 4.14 mL/kg to 17.17 mL/kg of essential oil, while the samples of fruits in pulvere
contain 9.12 mL/kg to 14.13 mL/kg of essential oil. All analyzed samples meet pharmaceutical
quality standards, as they contain at least 3 mL/kg of essential oil according to pharmacopoeial
requirements. The analysis of the isolated essential oil, performed using gas chromatography coupled
with tandem mass spectrometry (GC-MS/MS), showed that the main component of coriander
essential oil is linalool (61.83% - 87.73%). Other significantly represented components include γ-
terpinene (3.29% - 9.32%), α-pinene (0.74% - 7.15%), camphor (4.08% - 6.12%), geranyl acetate
(2.96% - 6.29%), p-cymene (0.74% - 3.01%), limonene (0.60% - 4.10%), geraniol (0.15% - 3.50%),
and α-terpineol (0.30% - 0.50%). This study emphasizes the importance of the quality of herbal drugs
used in phytotherapy and aromatherapy to ensure their effective and safe use. |
