prikaz prve stranice dokumenta Novel ureidoamides derived from amino acids: synthesis and preliminary biological screening
  Preuzmi
PDF 2.03 MB
Znanstveni rad - Izvorni znanstveni rad
Novel ureidoamides derived from amino acids: synthesis and preliminary biological screening
Croatica Chemica Acta, 83 (2010), 2; 151-161. urn:nbn:hr:163:634730
Perković, Ivana; Butula, Ivan; Rajić, Zrinka; Hadjipavlou-Litina, Dimitra; Pontiki, Eleni; Zorc, Branka

Citirajte ovaj rad

Perković, I., Butula, I., Rajić, Z., Hadjipavlou Litina, D., Pontiki, E. i Zorc, B. (2010). Novel ureidoamides derived from amino acids: synthesis and preliminary biological screening. Croatica Chemica Acta, 83. (2), 151-161. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:163:634730

Perković, Ivana, et al. "Novel ureidoamides derived from amino acids: synthesis and preliminary biological screening." Croatica Chemica Acta, vol. 83, br. 2, 2010, str. 151-161. https://urn.nsk.hr/urn:nbn:hr:163:634730

Perković, Ivana, Ivan Butula, Zrinka Rajić, Dimitra Hadjipavlou Litina, Eleni Pontiki i Branka Zorc. "Novel ureidoamides derived from amino acids: synthesis and preliminary biological screening." Croatica Chemica Acta 83, br. 2 (2010): 151-161. https://urn.nsk.hr/urn:nbn:hr:163:634730

Perković, I., et al. (2010) 'Novel ureidoamides derived from amino acids: synthesis and preliminary biological screening', Croatica Chemica Acta, 83(2), str. 151-161. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:163:634730 (Datum pristupa: 12.11.2024.)

Perković I, Butula I, Rajić Z, Hadjipavlou Litina D, Pontiki E, Zorc B. Novel ureidoamides derived from amino acids: synthesis and preliminary biological screening. Croatica Chemica Acta [Internet]. 15.07.2010. [pristupljeno 12.11.2024.];83(2):151-161. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:163:634730

I. Perković, I. Butula, Z. Rajić, D. Hadjipavlou Litina, E. Pontiki i B. Zorc, "Novel ureidoamides derived from amino acids: synthesis and preliminary biological screening", Croatica Chemica Acta, vol. 83, br. 2, str. 151-161, Srpanj 2010. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:163:634730. [Citirano: 12.11.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:163:634730
Prijavite se u repozitorij kako biste mogli spremiti objekt u svoju listu.
Podaci o radu
Naslov (engleski)Novel ureidoamides derived from amino acids: synthesis and preliminary biological screening
AutorIvana Perković
AutorIvan Butula
MBZ: 6372
AutorZrinka Rajić
AutorDimitra Hadjipavlou-Litina
AutorEleni Pontiki
AutorBranka Zorc
Autorova ustanovaSveučilište u Zagrebu
Farmaceutsko-biokemijski fakultet
(Zavod za farmaceutsku kemiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Farmacija
Farmacija
Sažetak (engleski)
A series of novel amino acid ureidoamides 4a-o were prepared from N-(1-benzotriazolecarbonyl)- amino acid chloride 3, derived from L-alanine, L-valine, L-leucine, D-phenylglycine and L-phenylalanine, and the corresponding aminoalcohols (2-amino-1-ethanol, 3-amino-1-propanol and 5-amino-1-pentanol). The compounds were fully characterized by standard spectroscopic methods (IR, 1H and 13C NMR) and their structure was confirmed by elemental analysis. Antioxidant screenings (interaction with 1,1-diphenyl-2-picrylhydrazyl, soybean lipoxygenase inhibition activity, inhibition of linoleic acid lipid peroxidation) revealed that the prepared compounds possessed only modest activity. On the other hand, no significant antiproliferative activity against five human cell lines and very weak antimicrobial activity against several bacteria and fungi were detected.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCroatica Chemica Acta
Brojčani podacivol. 83, br. 2, str. 151-161
p-ISSN0011-1643
e-ISSN1334-417X
URN:NBNurn:nbn:hr:163:634730
Datum objave publikacije2010-07-15
URL dokumentahttps://hrcak.srce.hr/56018
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2018-02-14 13:29:54