Suhi ekstrakt plodova sikavice (Silybum marianum (L.) Gaertn.) - terapeutik jetre

Stručni rad - Stručni rad

• Autor: Danica Kuštrak; MBZ: 126103
• Autorova ustanova: Sveučilište u Zagrebu; Farmaceutsko-biokemijski fakultet; (Zavod za farmakognoziju)
• Znanstveno / umjetničko područje, polje i grana: BIOMEDICINA I ZDRAVSTVO; Farmacija; Farmacija

Sažetak (engleski)

The milk thistle, Silybum marianum (L.) Gaertn. (= Carduus marianus
L.) belongs to the Asteraceae family. The history of this medicinal plant is
going back to· the time of the birth of Christ. It's fruits, Fructus Cardui Mariae,
commonly known as seeds, were formerly employed as a herbal remedy, while
nowdays they or their products in effective dosage are recognized as a therapeutic
agent. Wagner et al. (1968) were found in fruits of the milk thistle a group of flavonoid
compounds. These compounds were given the name silymarin. Further studies
showed that silymarin consists of three isomeric compounds: silibinin, silidianin
and silicristin (molecular formula: C,){,.0,., MW 482.45)
The positive effect of silymarin on elevated serum enzyme levels - an indication of
parenchymal damage in patients with chronic liver diseases -has been clearly apparent
in various nonblind controlled trials.
Indicatons of silymarin: toxic liver damage, for supportive treatment in chronic inflammatory
liver diseases and cirrhosis.

• Ključne riječi (hrvatski): sikavica; Silybum marianum (L.) Gaertn.; silimarin; jetra; hepatoterapija
• Jezik: hrvatski
• Vrsta publikacije: Stručni rad - Stručni rad
• Status objave: Objavljen
• Vrsta recenzije: Recenziran - domaća recenzija
• Verzija publikacije: Objavljena verzija rada (izdavačev PDF)
• Naslov časopisa: Farmaceutski glasnik
• Brojčani podaci: vol. 56, br. 6, str. 183-187
• p-ISSN: 0014-8202
• URN:NBN: urn:nbn:hr:163:384237
• Datum objave publikacije: 2000
• Vrsta resursa: Tekst
• Prava pristupa: Otvoreni pristup
• Datum i vrijeme pohrane: 2021-03-05 14:31:08